Biosynthesis of polyhydroxyalkanoates containing 2-hydroxybutyrate from unrelated carbon source by metabolically engineered Escherichia coli

We have previously reported in vivo biosynthesis of polylactic acid (PLA) and poly(3-hydroxybutyrate- co -lactate) [P(3HB -co- LA)] employing metabolically engineered Escherichia coli strains by the introduction of evolved Clostridium propionicum propionyl-CoA transferase (Pct Cp ) and Pseudomonas s...

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Veröffentlicht in:	Applied microbiology and biotechnology 2012-01, Vol.93 (1), p.273-283
Hauptverfasser:	Park, Si Jae, Lee, Tae Woo, Lim, Sung-Chul, Kim, Tae Wan, Lee, Hyuk, Kim, Min Kyung, Lee, Seung Hwan, Song, Bong Keun, Lee, Sang Yup
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Hydroxybutyric Acid - metabolism Applied Genetics and Molecular Biotechnology Biomedical and Life Sciences Biosynthesis Biotechnology Carbon Carbon - metabolism Carbon sources Cloning Clostridium - enzymology Clostridium - genetics Clostridium propionicum Culture Media - chemistry Cupriavidus necator - enzymology Cupriavidus necator - genetics Dehydrogenases E coli Engineering Escherichia coli - enzymology Escherichia coli - genetics Escherichia coli - metabolism Fermentation Genes Genetic engineering Genomes Glucose Hydroxybutyrates - metabolism Lactates - metabolism Lactococcus lactis Life Sciences Metabolic Engineering Metabolism Microbial Genetics and Genomics Microbiology Plasmids Polyhydroxyalkanoates Polyhydroxyalkanoates - metabolism Polylactic acid Polymerization Polymers Pseudomonas - enzymology Pseudomonas - genetics R&D Recombinant Proteins - genetics Recombinant Proteins - metabolism Research & development Research centers Research parks Studies
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