Associations of polymorphisms of folate cycle enzymes and risk of breast cancer in a Brazilian population are age dependent

Polymorphisms in genes involved in folate metabolism have been shown to be implicated in breast cancer risk but with contradictory results. In this case–control study, we investigated the association between MTHFR C677T and A1298C, TYMS 5′-UTR, MTR A2756G and c SHMT C1420T and also the folate carrie...

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Veröffentlicht in:	Molecular biology reports 2012-04, Vol.39 (4), p.4899-4907
Hauptverfasser:	Carvalho Barbosa, Rita de Cássia, Menezes, Débora Costa, Freire, Thiago Fernando Vasconcelos, Sales, Diogo Campos, Alencar, Victor Hugo Medeiros, Rabenhorst, Silvia Helena Barem
Format:	Artikel
Sprache:	eng
Schlagworte:	5' Untranslated Regions - genetics Adult Aged Aging - pathology Animal Anatomy Animal Biochemistry Biomedical and Life Sciences Brazil Breast cancer Breast Neoplasms - enzymology Breast Neoplasms - genetics Breast Neoplasms - pathology Enzymes Female Folic Acid - metabolism Gene Frequency - genetics Genetic Association Studies Genetic Predisposition to Disease Genetics, Population Genotype & phenotype Histology Humans Life Sciences Metabolism Middle Aged Morphology Neoplasm Staging Polymerase Chain Reaction Polymorphism Polymorphism, Single Nucleotide - genetics Risk Factors Vitamin B
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