Studies of Interaction Between Cyanine Dye T-284 and Fibrillar Alpha-Synuclein

A key feature of Parkinson’s disease is the formation and accumulation of amyloid fibrils of the natively unfolded protein α-synuclein (ASN) inside neurons. Recently we have proposed novel sensitive monomethinecyanine dye T-284 as fluorescent probe for quantitative detection of ASN amyloid fibrils....

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Veröffentlicht in:	Journal of fluorescence 2010-11, Vol.20 (6), p.1267-1274
Hauptverfasser:	Volkova, Kateryna D., Kovalska, Vladyslava B., Yu. Losytskyy, Mykhaylo, Veldhuis, Gertjan, Segers-Nolten, G. M. J., Tolmachev, Olexiy I., Subramaniam, Vinod, Yarmoluk, Sergiy M.
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Synuclein - chemistry Analytical Chemistry Anisotropy Atomic force microscopy Binding Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biomedicine Biophysics Biotechnology Carbocyanines - chemistry Decay Dyes Fluorescence Fluorescence Polarization Fluorescent Dyes - chemistry Microscopy, Atomic Force Molecular Structure Original Paper Proteins Running
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