Oral Fluorescence Imaging Using 405-nm Excitation, Aiding the Discrimination of Cancers and Precancers by Identifying Changes in Collagen and Elastic Breakdown and Neovascularization in the Underlying Stroma

Abstract Background Optical spectroscopy and imaging devices are being developed and tested for the screening and diagnosis of cancer and precancer in multiple organ sites. Objective The aim of the study reported here is to optimize the capability of an optical imaging device to discriminate precanc...

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