Blood platelet biochemistry

Abstract Defects in platelet function or formation increase the risk for bleeding or thrombosis, which indicates the crucial role for platelets in maintaining haemostasis in normal life. Upon vascular injury, platelets instantly adhere to the exposed extracellular matrix which results in platelet ac...

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Veröffentlicht in:	Thrombosis research 2012-03, Vol.129 (3), p.245-249
Hauptverfasser:	Broos, Katleen, De Meyer, Simon F, Feys, Hendrik B, Vanhoorelbeke, Karen, Deckmyn, Hans
Format:	Artikel
Sprache:	eng
Schlagworte:	activation aggregation Animals Biological and medical sciences Blood and lymphatic vessels Blood coagulation. Blood cells Blood Platelets - metabolism Cardiology. Vascular system Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Fundamental and applied biological sciences. Psychology Hematology, Oncology and Palliative Medicine Hemostasis Humans Integrin alpha2beta1 - blood Medical sciences Membrane Glycoproteins - blood Molecular and cellular biology Platelet Platelet Activation Platelet adhesion Platelet Adhesiveness Platelet Aggregation Platelet Glycoprotein GPIb-IX Complex Platelet Membrane Glycoproteins - metabolism secretion Signal Transduction Thrombosis - blood Thrombosis - prevention & control von Willebrand Factor - metabolism
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