New method to differentiate human peripheral blood monocytes into insulin producing cells: Human hematosphere culture

► Human BBHS contained many nestin-positive cells but few insulin-positive cells. ► NPCs in BBHS form islet-like clusters during four stages of IPC differentiation protocol. ► BBHS derived islet-like clusters resulting in emergence of many IPCs. ► Pancreatic β cell-specific genes are turned on in IP...

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