Subthalamic deep brain stimulation with a constant-current device in Parkinson's disease: an open-label randomised controlled trial

Summary Background The effects of constant-current deep brain stimulation (DBS) have not been studied in controlled trials in patients with Parkinson's disease. We aimed to assess the safety and efficacy of bilateral constant-current DBS of the subthalamic nucleus. Methods This prospective, ran...

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Veröffentlicht in:	Lancet neurology 2012-02, Vol.11 (2), p.140-149
Hauptverfasser:	Okun, Michael S, Dr, Gallo, Bruno V, MD, Mandybur, George, MD, Jagid, Jonathan, MD, Foote, Kelly D, MD, Revilla, Fredy J, MD, Alterman, Ron, MD, Jankovic, Joseph, MD, Simpson, Richard, MD, Junn, Fred, MD, Verhagen, Leo, MD, Arle, Jeff E, MD, Ford, Blair, MD, Goodman, Robert R, MD, Stewart, R Malcolm, MD, Horn, Stacy, DO, Baltuch, Gordon H, MD, Kopell, Brian H, MD, Marshall, Frederick, MD, Peichel, DeLea, BS, Pahwa, Rajesh, MD, Lyons, Kelly E, PhD, Tröster, Alexander I, PhD, Vitek, Jerrold L, MD, Tagliati, Michele, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Deep brain stimulation Deep Brain Stimulation - adverse effects Deep Brain Stimulation - instrumentation Deep Brain Stimulation - methods Diaries Dyskinesia Dyskinesias - therapy Electrodes, Implanted Female Follow-Up Studies Humans Male Middle Aged Movement disorders Neurology Parkinson Disease - physiopathology Parkinson Disease - therapy Parkinson's disease Patients Prospective Studies Severity of Illness Index Subthalamic Nucleus - surgery Treatment Outcome
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