αLβ2 Integrin is indispensable for CD8+ T-cell recruitment in experimental pancreatic and hepatocellular cancer

Recruitment of activated leukocytes from peripheral blood into the tumor tissue is a crucial step of the immune response, which is controlled by the interaction between specific adhesion molecules such as endothelial ICAM‐1 and leukocyte β2‐integrins. Although attenuated expression of adhesion molec...

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Veröffentlicht in:International journal of cancer 2012-05, Vol.130 (9), p.2067-2076
Hauptverfasser: Takeichi, Takayuki, Mocevicius, Paulius, Deduchovas, Olegas, Salnikova, Olga, Castro-Santa, Edward, Büchler, Markus W., Schmidt, Jan, Ryschich, Eduard
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Sprache:eng
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