A distinct microvascular endothelial gene expression profile in severe IUGR placentas

Abstract The placental microvasculature is essential for efficient transfer of gases, nutrients and waste between the mother and fetus. Microvascular hypoplasia of the terminal villi is a common pathology in severe Intra Uterine Growth Restriction (IUGR). We used novel methods to obtain placental mi...

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Veröffentlicht in:	Placenta (Eastbourne) 2012-04, Vol.33 (4), p.285-293
Hauptverfasser:	Dunk, C.E, Roggensack, A.M, Cox, B, Perkins, J.E, Åsenius, F, Keating, S, Weksberg, R, Kingdom, J.C.P, Adamson, S.L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antigens, CD - genetics Antigens, CD - metabolism Biological and medical sciences Butyrophilins Cohort Studies Embryology: invertebrates and vertebrates. Teratology Endothelium Endothelium, Vascular - metabolism Endothelium, Vascular - pathology Female Fetal growth retardation Fetal Growth Retardation - metabolism Fetal Growth Retardation - pathology Fundamental and applied biological sciences. Psychology Gene Expression Profiling Gene Expression Regulation, Developmental Humans Internal Medicine Membrane Glycoproteins - genetics Membrane Glycoproteins - metabolism Microarray analysis Microvessels Microvessels - metabolism Microvessels - pathology Obstetrics and Gynecology Oligonucleotide Array Sequence Analysis Placenta Placenta - blood supply Placenta - pathology Pre-Eclampsia - metabolism Pre-Eclampsia - pathology Preeclampsia Pregnancy Premature Birth - metabolism Premature Birth - pathology Receptor, trkB - genetics Receptor, trkB - metabolism Receptors, Cell Surface - genetics Receptors, Cell Surface - metabolism RNA, Messenger - metabolism Serum Amyloid A Protein - genetics Serum Amyloid A Protein - metabolism Severity of Illness Index Signaling Lymphocytic Activation Molecule Family Member 1 Young Adult
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