Allosteric Modulation of Seven Transmembrane Spanning Receptors: Theory, Practice, and Opportunities for Central Nervous System Drug Discovery
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| Veröffentlicht in: | Journal of medicinal chemistry 2012-02, Vol.55 (4), p.1445-1464 |
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| Sprache: | eng |
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| container_end_page | 1464 |
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| container_issue | 4 |
| container_start_page | 1445 |
| container_title | Journal of medicinal chemistry |
| container_volume | 55 |
| creator | Melancon, Bruce J Hopkins, Corey R Wood, Michael R Emmitte, Kyle A Niswender, Colleen M Christopoulos, Arthur Conn, P. Jeffrey Lindsley, Craig W |
| description | |
| doi_str_mv | 10.1021/jm201139r |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0022-2623 |
| ispartof | Journal of medicinal chemistry, 2012-02, Vol.55 (4), p.1445-1464 |
| issn | 0022-2623 1520-4804 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_923574786 |
| source | MEDLINE; American Chemical Society Journals |
| subjects | Allosteric Regulation Animals Central Nervous System Agents - chemistry Central Nervous System Agents - pharmacology Drug Discovery Humans Ligands Receptors, G-Protein-Coupled - agonists Receptors, G-Protein-Coupled - antagonists & inhibitors Receptors, G-Protein-Coupled - metabolism Receptors, Metabotropic Glutamate - metabolism Receptors, Muscarinic - metabolism Structure-Activity Relationship |
| title | Allosteric Modulation of Seven Transmembrane Spanning Receptors: Theory, Practice, and Opportunities for Central Nervous System Drug Discovery |
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