Dendritic cell-based vaccine in advanced melanoma: update of clinical outcome

Dendritic cells (DCs) are unique specialized antigen-presenting cells capable of priming naive T cells and inducing antigen-specific cytotoxic T lymphocytes. This study presents an update of clinical results from a DC-based phase I-II clinical vaccine trial in stage IV melanoma. From 2003 to 2010, 2...

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Veröffentlicht in:	Melanoma research 2011-12, Vol.21 (6), p.524-529
Hauptverfasser:	Ridolfi, Laura, Petrini, Massimiliano, Fiammenghi, Laura, Granato, Anna Maria, Ancarani, Valentina, Pancisi, Elena, Brolli, Claudia, Selva, Mirna, Scarpi, Emanuela, Valmorri, Linda, Nicoletti, Stefania Vittoria Luisa, Guidoboni, Massimo, Riccobon, Angela, Ridolfi, Ruggero
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Cancer Vaccines - therapeutic use Clinical Trials, Phase I as Topic Clinical Trials, Phase II as Topic Dendritic Cells - immunology Disease Progression Female Follow-Up Studies Humans Immunotherapy, Adoptive - methods Male Melanoma - diagnosis Melanoma - mortality Melanoma - pathology Melanoma - therapy Middle Aged Neoplasm Staging Prognosis Retrospective Studies Skin Neoplasms - diagnosis Skin Neoplasms - mortality Skin Neoplasms - pathology Skin Neoplasms - therapy Survival Analysis Treatment Outcome
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