Independent genetic loci for sensorimotor gating and attentional performance in BXD recombinant inbred strains

A startle reflex in response to an intense acoustic stimulus is inhibited when a barely detectable pulse precedes the startle stimulus by 30–500 ms. It has been theorized that this phenomenon, named prepulse inhibition (PPI) of a startle response, is an automatic early‐stage gating process contribut...

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Veröffentlicht in:	Genes, brain and behavior brain and behavior, 2012-03, Vol.11 (2), p.147-156
Hauptverfasser:	Loos, M., Staal, J., Pattij, T., Smit, A. B., Spijker, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	5‐CSRTT Acoustic Stimulation ADHD Animals Attention Attention - physiology Auditory stimuli Behavior, Animal - physiology C57BL/6J chromosome 16 chromosome 17 DBA/2J Decision Making - physiology five‐choice serial reaction time task Gating Gene loci Genetic control Genetic Loci Genotype Inbreeding lapses in attention Mental disorders Mice Mice, Inbred Strains mouse Quantitative Trait Loci Reaction Time - genetics Reaction time task Reflex - genetics Reflex, Startle - genetics Reflexes Rodents Schizophrenia Sensorimotor gating Sensory Gating - genetics Species Specificity Startle response
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