High-Frequency Field Stimulation of Primary Neurons Enhances Ryanodine Receptor-Mediated Ca super(2+) Release and Generates Hydrogen Peroxide, Which Jointly Stimulate NF- Kappa B Activity

Neuronal electrical activity increases intracellular Ca super(2+) concentration and generates reactive oxygen species. Here, we show that high frequency field stimulation of primary hippocampal neurons generated Ca super(2+) signals with an early and a late component, and promoted hydrogen peroxide...

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Veröffentlicht in:	Antioxidants & redox signaling 2011-04, Vol.14 (7), p.1245-1259
Hauptverfasser:	Riquelme, D, Alvarez, A, Leal, N, Adasme, T, Espinoza, I, Valdes, JA, Troncoso, N, Hartel, S, Hidalgo, J, Hidalgo, C, Carrasco, MA
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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