Modeling of dispersed-drug delivery from planar polymeric systems: Optimizing analytical solutions

Analytical solutions for the case of controlled dispersed-drug release from planar non-erodible polymeric matrices, based on Refined Integral Method, are presented. A new adjusting equation is used for the dissolved drug concentration profile in the depletion zone. The set of equations match the ava...

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Veröffentlicht in:	International journal of pharmaceutics 2010-11, Vol.400 (1), p.131-137
Hauptverfasser:	Helbling, Ignacio M., Ibarra, Juan C.D., Luna, Julio A., Cabrera, María I., Grau, Ricardo J.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chemistry, Pharmaceutical Delayed-Action Preparations Diffusion Dispersed drug Drug Delivery Systems - methods Drug release General pharmacology Kinetics Mathematical modeling Medical sciences Models, Theoretical Moving front Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Polymers - chemistry Refined Integral Method Solubility Solutions
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