Polymorphisms in drug transporter genes ( ABCB1 , SLCO1B1 and ABCC2 ) and hepatitis induced by antituberculosis drugs

Summary Unusual drug accumulation is a common mechanism underlying serious drug-induced liver injury. Polymorphisms in three drug transporter genes ( ABCB1, SLCO1B1 and ABCC2 ) may be risk markers for hepatitis induced by the unusual accumulation of anti-tuberculosis drugs (ATDs). We therefore inves...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Tuberculosis (Edinburgh, Scotland) Scotland), 2012-01, Vol.92 (1), p.100-104
Hauptverfasser:	Kim, Sang-Hoon, Kim, Sang-Heon, Lee, Jae-Hyung, Lee, Byoung-Hoon, Kim, Youn-Seup, Park, Jae-Seuk, Jee, Young-Koo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Antitubercular Agents - administration & dosage Antitubercular Agents - adverse effects Antituberculosis drug Asian Continental Ancestry Group - genetics ATP Binding Cassette Transporter, Sub-Family B ATP-Binding Cassette, Sub-Family B, Member 1 - genetics Chemical and Drug Induced Liver Injury - epidemiology Chemical and Drug Induced Liver Injury - genetics Drug transporter Female Hepatitis Humans Infectious Disease Male Middle Aged Multidrug Resistance-Associated Proteins - genetics Mycobacterium Organic Anion Transporters - genetics Polymorphism, Single Nucleotide Pulmonary/Respiratory Republic of Korea - epidemiology Risk Factors Solute Carrier Organic Anion Transporter Family Member 1b1 Tuberculosis, Pulmonary - drug therapy Tuberculosis, Pulmonary - epidemiology Tuberculosis, Pulmonary - genetics Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!