Dynamics of expression patterns of AQP4, dystroglycan, agrin and matrix metalloproteinases in human glioblastoma

In human glioblastoma, the blood–brain barrier (BBB) is disturbed. According to our concept, the glio-vascular relationships and thus the control of the BBB are essentially dependent on the polarity of astroglial cells. This polarity is characterized by the uneven distribution of the water channel p...

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Veröffentlicht in:	Cell and tissue research 2012-02, Vol.347 (2), p.429-441
Hauptverfasser:	Noell, Susan, Wolburg-Buchholz, Karen, Mack, Andreas F, Ritz, Rainer, Tatagiba, Marcos, Beschorner, Rudi, Wolburg, Hartwig, Fallier-Becker, Petra
Format:	Artikel
Sprache:	eng
Schlagworte:	agrin Agrin - metabolism Aquaporin 4 Aquaporin 4 - metabolism Aquaporins Astrocytes Biomedical and Life Sciences Biomedicine Blood-brain barrier Blood-Brain Barrier - metabolism Brain - metabolism Brain Neoplasms - metabolism Cell Polarity Dystroglycan Dystroglycans - metabolism Edema Electron microscopy Extracellular matrix Extracellular Matrix - metabolism Freeze Fracturing Freeze-fracture Gelatinase A Gene expression Glioblastoma Glioblastoma - metabolism Glioblastoma multiforme Glioma cells Human Genetics Humans Immunohistochemistry Matrix metalloproteinase Matrix Metalloproteinases - metabolism metalloproteinases Microscopy, Electron Molecular Medicine neoplasms Polarity Proteins Proteomics Regular Article Tumors water distribution Western blotting
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