Screening for Lynch Syndrome in Colorectal Cancer: Are We Doing Enough?

Purpose The purpose of this study was to assess the efficacy of screening for the detection of Lynch syndrome (LS) in an unselected population undergoing surgery for a colorectal cancer. Methods A total of 1,040 patients were prospectively included between 2005 and 2009. LS screening modalities incl...

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Veröffentlicht in:	Annals of surgical oncology 2012-03, Vol.19 (3), p.809-816
Hauptverfasser:	Canard, Guillaume, Lefevre, Jeremie H., Colas, Chrystelle, Coulet, Florence, Svrcek, Magali, Lascols, Olivier, Hamelin, Richard, Shields, Conor, Duval, Alex, Fléjou, Jean-Francois, Soubrier, Florent, Tiret, Emmanuel, Parc, Yann
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - analysis Adult Aged Aged, 80 and over Colorectal Cancer Colorectal Neoplasms - surgery Colorectal Neoplasms, Hereditary Nonpolyposis - diagnosis DNA Methylation DNA-Binding Proteins Female Genetic Testing Germ-Line Mutation Humans Immunohistochemistry Male Medicine Medicine & Public Health Microsatellite Instability Middle Aged MutL Protein Homolog 1 MutS Homolog 2 Protein - analysis Nuclear Proteins - analysis Oncology Promoter Regions, Genetic Surgery Surgical Oncology Young Adult
Online-Zugang:	Volltext
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