INO1 induction requires chromatin remodelers Ino80p and Snf2p but not the histone acetylases

► We examine the recruitment of transcriptional co-activators during INO1 induction. ► Ino2p is required to recruit co-activators during INO1 activation. ► Both Ino80p and Snf2p remodelers contribute to the additive recruitment of Gcn5p. ► The histone acetylases are dispensable in INO1 induction. Tr...

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Veröffentlicht in:	Biochemical and biophysical research communications 2012-02, Vol.418 (3), p.483-488
Hauptverfasser:	Konarzewska, Paulina, Esposito, Michelle, Shen, Chang-Hui
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - genetics Adenosine Triphosphatases - metabolism Chromatin Chromatin Assembly and Disassembly Gene Expression Regulation, Enzymologic Gene Expression Regulation, Fungal Gene regulation Histone Acetyltransferases - genetics Histone Acetyltransferases - metabolism Immunoprecipitation INO1 Ino2p Myo-Inositol-1-Phosphate Synthase - genetics Real-Time Polymerase Chain Reaction Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Transcription Factors - genetics Transcription Factors - metabolism Transcriptional Activation Transcriptional co-activator
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