Expression of Telomeres in Astrocytoma WHO Grade 2 to 4: TERRA Level Correlates with Telomere Length, Telomerase Activity, and Advanced Clinical Grade

Cancer cells bypass replicative senescence, the major barrier to tumor progression, by using telomerase or alternative lengthening of telomeres (ALT) as telomere maintenance mechanisms (TMMs). Correlation between ALT and patient survival was demonstrated for high-grade astrocytomas. Transcription fr...

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Veröffentlicht in:	Translational oncology 2012-02, Vol.5 (1), p.56-IN4
Hauptverfasser:	Sampl, Sandra, Pramhas, Sibylle, Stern, Christian, Preusser, Matthias, Marosi, Christine, Holzmann, Klaus
Format:	Artikel
Sprache:	eng
Schlagworte:	Oncology
Online-Zugang:	Volltext
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