Probing quenched dye fluorescence of Cy3–DNA–Au-nanoparticle hybrid conjugates using solution and array platforms

[Display omitted] ► Au–DNA–Cy3 prepared using 10-nm AuNPs and ds-DNA with disulfide-modified target and Cy3-labeled probe. ► Quenching of Au–DNA–Cy3 in solution and array platforms assessed using ligand exchange by ME. ► High quenching efficiency observed for the shortest Au-to-Cy3 gap. Tuning the l...

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