innate antiviral factor APOBEC3G targets replication of measles, mumps and respiratory syncytial viruses

The cytidine deaminase APOBEC3G (apolipoprotein B mRNA-editing enzyme-catalytic polypeptide 3G; A3G) exerts antiviral activity against retroviruses, hepatitis B virus, adeno-associated virus and transposable elements. We assessed whether the negative-strand RNA viruses measles, mumps and respiratory...

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Veröffentlicht in:	Journal of general virology 2012-03, Vol.93 (Pt 3), p.565-576
Hauptverfasser:	Fehrholz, Markus, Kendl, Sabine, Prifert, Christiane, Weissbrich, Benedikt, Lemon, Ken, Rennick, Linda, Duprex, Paul W, Rima, Bert K, Koning, Fransje A, Holmes, Rebecca K, Malim, Michael H, Schneider-Schaulies, Jürgen
Format:	Artikel
Sprache:	eng
Schlagworte:	adenine adenosine deaminase Animals Antiviral Agents - metabolism antiviral properties APOBEC-3G Deaminase apolipoprotein B Biological and medical sciences Cell Line coprecipitation cytidine cytidine deaminase Cytidine Deaminase - immunology Cytidine Deaminase - metabolism Fundamental and applied biological sciences. Psychology gene overexpression guanine Hepatitis B virus Humans Measles virus - growth & development Measles virus - immunology Measles virus - pathogenicity Microbiology Miscellaneous Mumps virus - growth & development Mumps virus - immunology Mumps virus - pathogenicity mutants mutation pathogenicity Point Mutation polypeptides protein synthesis Respiratory Syncytial Viruses - growth & development Respiratory Syncytial Viruses - immunology Respiratory Syncytial Viruses - pathogenicity Retroviridae reverse transcriptase polymerase chain reaction RNA RNA, Viral - genetics T-lymphocytes transposons uridine Virology Virus Replication viruses
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