Morphometry of the orbital region soft tissues in Down syndrome

The orbital region of subjects with Down syndrome (DS) has been scanty described so far. We wanted to detail the morphologic characteristics of the soft tissue orbital region in Italian and North Sudanese subjects with DS. The three-dimensional coordinates of 10 landmarks on the orbital soft tissues...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The Journal of craniofacial surgery 2012-01, Vol.23 (1), p.198-202
Hauptverfasser: Sforza, Chiarella, Elamin, Fadil, Dellavia, Claudia, Rosati, Riccardo, Lodetti, Gianluigi, Mapelli, Andrea, Ferrario, Virgilio Ferruccio
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 202
container_issue 1
container_start_page 198
container_title The Journal of craniofacial surgery
container_volume 23
creator Sforza, Chiarella
Elamin, Fadil
Dellavia, Claudia
Rosati, Riccardo
Lodetti, Gianluigi
Mapelli, Andrea
Ferrario, Virgilio Ferruccio
description The orbital region of subjects with Down syndrome (DS) has been scanty described so far. We wanted to detail the morphologic characteristics of the soft tissue orbital region in Italian and North Sudanese subjects with DS. The three-dimensional coordinates of 10 landmarks on the orbital soft tissues were obtained using computerized anthropometry in 53 Italian and 64 North Sudanese subjects with DS aged 4 to 52 years, and in 461 (Italian) and 682 (North Sudanese) sex- and age-matched controls. From the landmarks, linear distances, ratios, areas, and angles were calculated, z scores computed, and compared by t-tests and analyses of covariance. In North Sudanese DS subjects, intercanthal width and height-to-length ratio were increased; biorbital width, eye height, length, and area were reduced. Eye fissure and orbital inclinations relative to Frankfort plane were reduced, whereas orbital inclinations versus the true horizontal were increased. In Italian DS men, orbital height and height-to-length ratio were increased, eye length was decreased; orbital inclination versus the true horizontal was increased. For almost all measurements, a significant effect of age was found. No effects of sex were found. Ethnic group influenced orbital height, area, and orbital inclination versus Frankfort plane. All paired measurements had similar discrepancies on both sides. The orbital soft tissues of North Sudanese DS subjects differed from those of their reference subjects, but this was only partially true for Italian subjects. The 2 ethnic groups had different alterations in their soft tissue orbital regions that were influenced by age, but not by sex.
doi_str_mv 10.1097/SCS.0b013e3182418eba
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_922215304</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>922215304</sourcerecordid><originalsourceid>FETCH-LOGICAL-c352t-5cc7ea0dcda3b2902d31e0e40e9b32a1e83004f9ac577a2931d899684b9af5333</originalsourceid><addsrcrecordid>eNpdkE9PwzAMxSMEYmPwDRDKjVNHYqdLc0Jo_JWGOAzOVdq6rKhtRtIJ7dsTtMGBky3rPfv5x9i5FFMpjL5azpdTUQiJhDIDJTMq7AEbyxRnCWqEw9gLZRIAnY7YSQgfQoCUMDtmIwBErYQes-tn59cr19Hgt9zVfFgRd75oBttyT--N63lw9cCHJoQNBd70_NZ9xeG2r3y0nbKj2raBzvZ1wt7u717nj8ni5eFpfrNISkxhSNKy1GRFVVYWCzACKpQkSAkyBYKVlKEQqja2TLW2YFBWmTGzTBXG1ikiTtjlbu_au88YZMi7JpTUtrYntwm5AYD4ulBRqXbK0rsQPNX52jed9dtcivyHXB7J5f_JRdvF_sCm6Kj6M_2iwm9GNGqv</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>922215304</pqid></control><display><type>article</type><title>Morphometry of the orbital region soft tissues in Down syndrome</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>Sforza, Chiarella ; Elamin, Fadil ; Dellavia, Claudia ; Rosati, Riccardo ; Lodetti, Gianluigi ; Mapelli, Andrea ; Ferrario, Virgilio Ferruccio</creator><creatorcontrib>Sforza, Chiarella ; Elamin, Fadil ; Dellavia, Claudia ; Rosati, Riccardo ; Lodetti, Gianluigi ; Mapelli, Andrea ; Ferrario, Virgilio Ferruccio</creatorcontrib><description>The orbital region of subjects with Down syndrome (DS) has been scanty described so far. We wanted to detail the morphologic characteristics of the soft tissue orbital region in Italian and North Sudanese subjects with DS. The three-dimensional coordinates of 10 landmarks on the orbital soft tissues were obtained using computerized anthropometry in 53 Italian and 64 North Sudanese subjects with DS aged 4 to 52 years, and in 461 (Italian) and 682 (North Sudanese) sex- and age-matched controls. From the landmarks, linear distances, ratios, areas, and angles were calculated, z scores computed, and compared by t-tests and analyses of covariance. In North Sudanese DS subjects, intercanthal width and height-to-length ratio were increased; biorbital width, eye height, length, and area were reduced. Eye fissure and orbital inclinations relative to Frankfort plane were reduced, whereas orbital inclinations versus the true horizontal were increased. In Italian DS men, orbital height and height-to-length ratio were increased, eye length was decreased; orbital inclination versus the true horizontal was increased. For almost all measurements, a significant effect of age was found. No effects of sex were found. Ethnic group influenced orbital height, area, and orbital inclination versus Frankfort plane. All paired measurements had similar discrepancies on both sides. The orbital soft tissues of North Sudanese DS subjects differed from those of their reference subjects, but this was only partially true for Italian subjects. The 2 ethnic groups had different alterations in their soft tissue orbital regions that were influenced by age, but not by sex.</description><identifier>ISSN: 1049-2275</identifier><identifier>EISSN: 1536-3732</identifier><identifier>DOI: 10.1097/SCS.0b013e3182418eba</identifier><identifier>PMID: 22337407</identifier><language>eng</language><publisher>United States</publisher><subject>Adolescent ; Adult ; African Continental Ancestry Group ; Age Factors ; Anatomic Landmarks - pathology ; Case-Control Studies ; Cephalometry - methods ; Child ; Child, Preschool ; Dentistry ; Down Syndrome - ethnology ; Down Syndrome - pathology ; Ear, External - pathology ; European Continental Ancestry Group ; Eye - pathology ; Eyelids - pathology ; Female ; Humans ; Image Processing, Computer-Assisted - methods ; Imaging, Three-Dimensional - methods ; Italy ; Lip - pathology ; Male ; Middle Aged ; Mouth - pathology ; Nose - pathology ; Orbit - pathology ; Sex Factors ; Sudan ; Young Adult</subject><ispartof>The Journal of craniofacial surgery, 2012-01, Vol.23 (1), p.198-202</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c352t-5cc7ea0dcda3b2902d31e0e40e9b32a1e83004f9ac577a2931d899684b9af5333</citedby><cites>FETCH-LOGICAL-c352t-5cc7ea0dcda3b2902d31e0e40e9b32a1e83004f9ac577a2931d899684b9af5333</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22337407$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sforza, Chiarella</creatorcontrib><creatorcontrib>Elamin, Fadil</creatorcontrib><creatorcontrib>Dellavia, Claudia</creatorcontrib><creatorcontrib>Rosati, Riccardo</creatorcontrib><creatorcontrib>Lodetti, Gianluigi</creatorcontrib><creatorcontrib>Mapelli, Andrea</creatorcontrib><creatorcontrib>Ferrario, Virgilio Ferruccio</creatorcontrib><title>Morphometry of the orbital region soft tissues in Down syndrome</title><title>The Journal of craniofacial surgery</title><addtitle>J Craniofac Surg</addtitle><description>The orbital region of subjects with Down syndrome (DS) has been scanty described so far. We wanted to detail the morphologic characteristics of the soft tissue orbital region in Italian and North Sudanese subjects with DS. The three-dimensional coordinates of 10 landmarks on the orbital soft tissues were obtained using computerized anthropometry in 53 Italian and 64 North Sudanese subjects with DS aged 4 to 52 years, and in 461 (Italian) and 682 (North Sudanese) sex- and age-matched controls. From the landmarks, linear distances, ratios, areas, and angles were calculated, z scores computed, and compared by t-tests and analyses of covariance. In North Sudanese DS subjects, intercanthal width and height-to-length ratio were increased; biorbital width, eye height, length, and area were reduced. Eye fissure and orbital inclinations relative to Frankfort plane were reduced, whereas orbital inclinations versus the true horizontal were increased. In Italian DS men, orbital height and height-to-length ratio were increased, eye length was decreased; orbital inclination versus the true horizontal was increased. For almost all measurements, a significant effect of age was found. No effects of sex were found. Ethnic group influenced orbital height, area, and orbital inclination versus Frankfort plane. All paired measurements had similar discrepancies on both sides. The orbital soft tissues of North Sudanese DS subjects differed from those of their reference subjects, but this was only partially true for Italian subjects. The 2 ethnic groups had different alterations in their soft tissue orbital regions that were influenced by age, but not by sex.</description><subject>Adolescent</subject><subject>Adult</subject><subject>African Continental Ancestry Group</subject><subject>Age Factors</subject><subject>Anatomic Landmarks - pathology</subject><subject>Case-Control Studies</subject><subject>Cephalometry - methods</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Dentistry</subject><subject>Down Syndrome - ethnology</subject><subject>Down Syndrome - pathology</subject><subject>Ear, External - pathology</subject><subject>European Continental Ancestry Group</subject><subject>Eye - pathology</subject><subject>Eyelids - pathology</subject><subject>Female</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted - methods</subject><subject>Imaging, Three-Dimensional - methods</subject><subject>Italy</subject><subject>Lip - pathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mouth - pathology</subject><subject>Nose - pathology</subject><subject>Orbit - pathology</subject><subject>Sex Factors</subject><subject>Sudan</subject><subject>Young Adult</subject><issn>1049-2275</issn><issn>1536-3732</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkE9PwzAMxSMEYmPwDRDKjVNHYqdLc0Jo_JWGOAzOVdq6rKhtRtIJ7dsTtMGBky3rPfv5x9i5FFMpjL5azpdTUQiJhDIDJTMq7AEbyxRnCWqEw9gLZRIAnY7YSQgfQoCUMDtmIwBErYQes-tn59cr19Hgt9zVfFgRd75oBttyT--N63lw9cCHJoQNBd70_NZ9xeG2r3y0nbKj2raBzvZ1wt7u717nj8ni5eFpfrNISkxhSNKy1GRFVVYWCzACKpQkSAkyBYKVlKEQqja2TLW2YFBWmTGzTBXG1ikiTtjlbu_au88YZMi7JpTUtrYntwm5AYD4ulBRqXbK0rsQPNX52jed9dtcivyHXB7J5f_JRdvF_sCm6Kj6M_2iwm9GNGqv</recordid><startdate>201201</startdate><enddate>201201</enddate><creator>Sforza, Chiarella</creator><creator>Elamin, Fadil</creator><creator>Dellavia, Claudia</creator><creator>Rosati, Riccardo</creator><creator>Lodetti, Gianluigi</creator><creator>Mapelli, Andrea</creator><creator>Ferrario, Virgilio Ferruccio</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201201</creationdate><title>Morphometry of the orbital region soft tissues in Down syndrome</title><author>Sforza, Chiarella ; Elamin, Fadil ; Dellavia, Claudia ; Rosati, Riccardo ; Lodetti, Gianluigi ; Mapelli, Andrea ; Ferrario, Virgilio Ferruccio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c352t-5cc7ea0dcda3b2902d31e0e40e9b32a1e83004f9ac577a2931d899684b9af5333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>African Continental Ancestry Group</topic><topic>Age Factors</topic><topic>Anatomic Landmarks - pathology</topic><topic>Case-Control Studies</topic><topic>Cephalometry - methods</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Dentistry</topic><topic>Down Syndrome - ethnology</topic><topic>Down Syndrome - pathology</topic><topic>Ear, External - pathology</topic><topic>European Continental Ancestry Group</topic><topic>Eye - pathology</topic><topic>Eyelids - pathology</topic><topic>Female</topic><topic>Humans</topic><topic>Image Processing, Computer-Assisted - methods</topic><topic>Imaging, Three-Dimensional - methods</topic><topic>Italy</topic><topic>Lip - pathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mouth - pathology</topic><topic>Nose - pathology</topic><topic>Orbit - pathology</topic><topic>Sex Factors</topic><topic>Sudan</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sforza, Chiarella</creatorcontrib><creatorcontrib>Elamin, Fadil</creatorcontrib><creatorcontrib>Dellavia, Claudia</creatorcontrib><creatorcontrib>Rosati, Riccardo</creatorcontrib><creatorcontrib>Lodetti, Gianluigi</creatorcontrib><creatorcontrib>Mapelli, Andrea</creatorcontrib><creatorcontrib>Ferrario, Virgilio Ferruccio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of craniofacial surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sforza, Chiarella</au><au>Elamin, Fadil</au><au>Dellavia, Claudia</au><au>Rosati, Riccardo</au><au>Lodetti, Gianluigi</au><au>Mapelli, Andrea</au><au>Ferrario, Virgilio Ferruccio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Morphometry of the orbital region soft tissues in Down syndrome</atitle><jtitle>The Journal of craniofacial surgery</jtitle><addtitle>J Craniofac Surg</addtitle><date>2012-01</date><risdate>2012</risdate><volume>23</volume><issue>1</issue><spage>198</spage><epage>202</epage><pages>198-202</pages><issn>1049-2275</issn><eissn>1536-3732</eissn><abstract>The orbital region of subjects with Down syndrome (DS) has been scanty described so far. We wanted to detail the morphologic characteristics of the soft tissue orbital region in Italian and North Sudanese subjects with DS. The three-dimensional coordinates of 10 landmarks on the orbital soft tissues were obtained using computerized anthropometry in 53 Italian and 64 North Sudanese subjects with DS aged 4 to 52 years, and in 461 (Italian) and 682 (North Sudanese) sex- and age-matched controls. From the landmarks, linear distances, ratios, areas, and angles were calculated, z scores computed, and compared by t-tests and analyses of covariance. In North Sudanese DS subjects, intercanthal width and height-to-length ratio were increased; biorbital width, eye height, length, and area were reduced. Eye fissure and orbital inclinations relative to Frankfort plane were reduced, whereas orbital inclinations versus the true horizontal were increased. In Italian DS men, orbital height and height-to-length ratio were increased, eye length was decreased; orbital inclination versus the true horizontal was increased. For almost all measurements, a significant effect of age was found. No effects of sex were found. Ethnic group influenced orbital height, area, and orbital inclination versus Frankfort plane. All paired measurements had similar discrepancies on both sides. The orbital soft tissues of North Sudanese DS subjects differed from those of their reference subjects, but this was only partially true for Italian subjects. The 2 ethnic groups had different alterations in their soft tissue orbital regions that were influenced by age, but not by sex.</abstract><cop>United States</cop><pmid>22337407</pmid><doi>10.1097/SCS.0b013e3182418eba</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1049-2275
ispartof The Journal of craniofacial surgery, 2012-01, Vol.23 (1), p.198-202
issn 1049-2275
1536-3732
language eng
recordid cdi_proquest_miscellaneous_922215304
source MEDLINE; Journals@Ovid Complete
subjects Adolescent
Adult
African Continental Ancestry Group
Age Factors
Anatomic Landmarks - pathology
Case-Control Studies
Cephalometry - methods
Child
Child, Preschool
Dentistry
Down Syndrome - ethnology
Down Syndrome - pathology
Ear, External - pathology
European Continental Ancestry Group
Eye - pathology
Eyelids - pathology
Female
Humans
Image Processing, Computer-Assisted - methods
Imaging, Three-Dimensional - methods
Italy
Lip - pathology
Male
Middle Aged
Mouth - pathology
Nose - pathology
Orbit - pathology
Sex Factors
Sudan
Young Adult
title Morphometry of the orbital region soft tissues in Down syndrome
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T01%3A22%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Morphometry%20of%20the%20orbital%20region%20soft%20tissues%20in%20Down%20syndrome&rft.jtitle=The%20Journal%20of%20craniofacial%20surgery&rft.au=Sforza,%20Chiarella&rft.date=2012-01&rft.volume=23&rft.issue=1&rft.spage=198&rft.epage=202&rft.pages=198-202&rft.issn=1049-2275&rft.eissn=1536-3732&rft_id=info:doi/10.1097/SCS.0b013e3182418eba&rft_dat=%3Cproquest_cross%3E922215304%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=922215304&rft_id=info:pmid/22337407&rfr_iscdi=true