Clinical significance of early T-cell precursor acute lymphoblastic leukaemia: results of the Tokyo Children's Cancer Study Group Study L99-15

Summary Early T‐cell precursor acute lymphoblastic leukaemia (ETP‐ALL) is a recently identified subtype of T‐ALL with distinctive gene expression and cell marker profiles, poor response to chemotherapy and a very high risk of relapse. We determined the reliability of restricted panel of cell markers...

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Veröffentlicht in:	British journal of haematology 2012-02, Vol.156 (3), p.358-365
Hauptverfasser:	Inukai, Takeshi, Kiyokawa, Nobutaka, Campana, Dario, Coustan-Smith, Elaine, Kikuchi, Akira, Kobayashi, Miyuki, Takahashi, Hiroyuki, Koh, Katsuyoshi, Manabe, Atsushi, Kumagai, Masaaki, Ikuta, Koichiro, Hayashi, Yasuhide, Tsuchida, Masahiro, Sugita, Kanji, Ohara, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	acute lymphoblastic leukaemia Adolescent allogeneic stem cell transplantation Antigens, CD - analysis Antigens, Neoplasm - analysis Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences cell marker profile Child Child, Preschool childhood Combined Modality Therapy Disease-Free Survival Drug Resistance, Neoplasm Early T-cell precursor Female Hematologic and hematopoietic diseases Humans Immunophenotyping Infant Japan - epidemiology Kaplan-Meier Estimate Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - classification Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - epidemiology Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - surgery Prednisone - administration & dosage Remission Induction Stem Cell Transplantation Transplantation, Homologous Treatment Outcome
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