Sun Exposure: What Molecular Photodermatology Tells Us About Its Good and Bad Sides
The health consequences of sun exposure have concerned mankind for more than 100 years. Recent molecular studies in photodermatology have greatly advanced our understanding of this important topic. We will illustrate this progress by focusing on the following selected topics: (i) the nature of the D...
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| Veröffentlicht in: | Journal of investigative dermatology 2012-03, Vol.132 (3), p.976-984 |
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| container_end_page | 984 |
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| container_title | Journal of investigative dermatology |
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| creator | Krutmann, Jean Morita, Akimichi Chung, Jin Ho |
| description | The health consequences of sun exposure have concerned mankind for more than 100 years. Recent molecular studies in photodermatology have greatly advanced our understanding of this important topic. We will illustrate this progress by focusing on the following selected topics: (i) the nature of the DNA damage–independent part of the UVB response of human skin and the role of the arylhydrocarbon receptor in cutaneous biology, (ii) the contribution of wavelengths beyond the UV spectrum to solar radiation–induced skin damage, (iii) the emerging evidence that subcutaneous fat is a target tissue for sunlight, and (iv) the most recent insight into the mode of action of phototherapy. |
| doi_str_mv | 10.1038/jid.2011.394 |
| format | Article |
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| ispartof | Journal of investigative dermatology, 2012-03, Vol.132 (3), p.976-984 |
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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Biological and medical sciences Dermatology DNA Damage - physiology Humans Medical sciences Phototherapy - trends Skin - metabolism Skin - radiation effects Skin Aging - physiology Sunlight - adverse effects Vitamin D - biosynthesis |
| title | Sun Exposure: What Molecular Photodermatology Tells Us About Its Good and Bad Sides |
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