Beta-adrenergic receptor polymorphisms associated with length of ICU stay in pediatric status asthmaticus

Background During severe exacerbations, asthmatic children vary significantly in their response to high‐dose continuous β2‐adrenergic receptor (ADRβ2) agonist therapy. Genetic polymorphisms have been identified within the ADRβ2 that may be functionally relevant, but few studies have been performed i...

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Veröffentlicht in:	Pediatric pulmonology 2012-03, Vol.47 (3), p.233-239
Hauptverfasser:	Carroll, Christopher L., Sala, Kathleen A., Zucker, Aaron R., Schramm, Craig M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent asthma Biological and medical sciences Child Child, Preschool Chronic obstructive pulmonary disease, asthma Cohort Studies Female General aspects genetics Genotype Haplotypes Hospitalization - statistics & numerical data Humans Intensive Care Units, Pediatric - statistics & numerical data Length of Stay - statistics & numerical data Male Medical sciences pediatrics Pneumology Polymorphism, Genetic Receptors, Adrenergic, beta-2 - genetics Severity of Illness Index Status Asthmaticus - genetics
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