Association of human adenovirus-36 in overweight Korean adults
Background: Although human adenovirus-36 (Ad-36) has been reported to be associated with obesity in US adults and children, Korean children and the Italian population, the association has not been found in Dutch or Belgian populations or in US military subjects. Therefore, we examined whether Ad-36...
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Veröffentlicht in: | International Journal of Obesity 2012-02, Vol.36 (2), p.281-285 |
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creator | Na, H-N Kim, J Lee, H S Shim, K W Kimm, H Jee, S H Jo, I Nam, J-H |
description | Background:
Although human adenovirus-36 (Ad-36) has been reported to be associated with obesity in US adults and children, Korean children and the Italian population, the association has not been found in Dutch or Belgian populations or in US military subjects. Therefore, we examined whether Ad-36 infection is associated with obesity in Korean adults.
Methods:
A total of 540 age- and sex-matched individuals, who were normal weight, overweight or obese, were selected from participants in routine health examinations at the Ewha Womans University Medical Center. Overweight participants were defined as those with a body mass index (BMI) of 23⩽BMI |
doi_str_mv | 10.1038/ijo.2011.102 |
format | Article |
fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_921568060</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A281374781</galeid><sourcerecordid>A281374781</sourcerecordid><originalsourceid>FETCH-LOGICAL-c582t-f27c7b6d46b8f67d32528a0584c280cfd8154fb2bc29ff0488bd7b9b0c97b203</originalsourceid><addsrcrecordid>eNp90c2P1CAYB2BiNO64evNsGo0fBzu-0PJ1MZls_IqbeNl7AxRmmLSwQrvG_166M7qu2RgODeXhhZcfQk8xrDE04p3fxzUBjMuM3EMr3HJW01by-2gFDfAaKKMn6FHOewCgFMhDdEIwFZxAs0LvNzlH49XkY6iiq3bzqEKlehvilU9zrhtW-bJyZdMP67e7qfoak70m8zDlx-iBU0O2T47fU3Tx8cPF2ef6_NunL2eb89pQQabaEW64Zn3LtHCM9w2hRCigojVEgHG9wLR1mmhDpHPQCqF7rqUGI7ku9zxFrw9lL1P8Pts8daPPxg6DCjbOuZOlISaALfLNfyUG3IKUEuNCn_9D93FOobSx1OPlEtfoxQFt1WA7H1yckjJLzW5DBG54y8Wi1neoMno7ehODdb78v7Xh1V8bdlYN0y7HYV5iyLfh2wM0KeacrOsukx9V-lk66Zb8u5J_t-RfZqTwZ8eeZj3a_g_-HXgBL49AZaMGl1QwPt84SiVrMCuuPrhclsLWppvHufPgX4Kqwkc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>921748811</pqid></control><display><type>article</type><title>Association of human adenovirus-36 in overweight Korean adults</title><source>MEDLINE</source><source>SpringerLink Journals</source><source>Nature Journals Online</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Na, H-N ; Kim, J ; Lee, H S ; Shim, K W ; Kimm, H ; Jee, S H ; Jo, I ; Nam, J-H</creator><creatorcontrib>Na, H-N ; Kim, J ; Lee, H S ; Shim, K W ; Kimm, H ; Jee, S H ; Jo, I ; Nam, J-H</creatorcontrib><description>Background:
Although human adenovirus-36 (Ad-36) has been reported to be associated with obesity in US adults and children, Korean children and the Italian population, the association has not been found in Dutch or Belgian populations or in US military subjects. Therefore, we examined whether Ad-36 infection is associated with obesity in Korean adults.
Methods:
A total of 540 age- and sex-matched individuals, who were normal weight, overweight or obese, were selected from participants in routine health examinations at the Ewha Womans University Medical Center. Overweight participants were defined as those with a body mass index (BMI) of 23⩽BMI<25 kg m
−2
and obese subjects were those with BMI⩾25 kg m
−2
, according to the International Obesity Task Force definition. Ad-36 antibody was measured using a serum neutralization assay.
Results:
Although more overweight participants than normal or obese subjects tested positive for the Ad-36 antibody (40%, 32.8% and 30%, respectively), the differences were not significant. The participants who tested positive for Ad-36 antibody had lower levels of triglycerides (TG) in each of the three groups, higher total cholesterol (TC) in the obese group and higher high-density lipoprotein-cholesterol (HDL-C) in both the normal and obese groups. The odds ratio (OR) for Ad-36 antibody positivity was greater in overweight than in normal subjects (OR=2.03; 95% confidence interval (CI), 1.16–3.55) after adjusting for age, sex and waist circumference. However, this OR was non-significant in the obese group (OR=1.56; 95% CI, 0.67–3.67).
Conclusion:
Ad-36 seems to be strongly associated with overweight, but not obese, Korean adults.</description><identifier>ISSN: 0307-0565</identifier><identifier>EISSN: 1476-5497</identifier><identifier>DOI: 10.1038/ijo.2011.102</identifier><identifier>PMID: 21587203</identifier><identifier>CODEN: IJOBDP</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Adenovirus diseases ; Adenovirus Infections, Human - blood ; Adenovirus Infections, Human - complications ; Adenovirus Infections, Human - epidemiology ; Adenovirus Infections, Human - immunology ; Adenoviruses ; Adenoviruses, Human - immunology ; Adipocytes ; Adult ; Adults ; Antibodies ; Asian Continental Ancestry Group - statistics & numerical data ; Biological and medical sciences ; Biomarkers - blood ; Body Mass Index ; Cardiovascular disease ; Case-Control Studies ; Cholesterol ; Cholesterol, HDL - blood ; Complications and side effects ; Cross-Sectional Studies ; Epidemiology ; Female ; Health aspects ; Health promotion ; Health Promotion and Disease Prevention ; Humans ; Internal Medicine ; Male ; Medical sciences ; Medicine ; Medicine & Public Health ; Metabolic Diseases ; Middle Aged ; Neutralization ; Nutrition research ; Obesity ; Obesity - virology ; Odds Ratio ; original-article ; Overweight ; Overweight - blood ; Overweight - epidemiology ; Overweight - immunology ; Overweight - virology ; Population ; Prevalence ; Public Health ; Republic of Korea - epidemiology ; Risk Factors ; Task forces ; Triglycerides - blood</subject><ispartof>International Journal of Obesity, 2012-02, Vol.36 (2), p.281-285</ispartof><rights>Macmillan Publishers Limited 2012</rights><rights>2015 INIST-CNRS</rights><rights>COPYRIGHT 2012 Nature Publishing Group</rights><rights>Copyright Nature Publishing Group Feb 2012</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c582t-f27c7b6d46b8f67d32528a0584c280cfd8154fb2bc29ff0488bd7b9b0c97b203</citedby><cites>FETCH-LOGICAL-c582t-f27c7b6d46b8f67d32528a0584c280cfd8154fb2bc29ff0488bd7b9b0c97b203</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/ijo.2011.102$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/ijo.2011.102$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25596316$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21587203$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Na, H-N</creatorcontrib><creatorcontrib>Kim, J</creatorcontrib><creatorcontrib>Lee, H S</creatorcontrib><creatorcontrib>Shim, K W</creatorcontrib><creatorcontrib>Kimm, H</creatorcontrib><creatorcontrib>Jee, S H</creatorcontrib><creatorcontrib>Jo, I</creatorcontrib><creatorcontrib>Nam, J-H</creatorcontrib><title>Association of human adenovirus-36 in overweight Korean adults</title><title>International Journal of Obesity</title><addtitle>Int J Obes</addtitle><addtitle>Int J Obes (Lond)</addtitle><description>Background:
Although human adenovirus-36 (Ad-36) has been reported to be associated with obesity in US adults and children, Korean children and the Italian population, the association has not been found in Dutch or Belgian populations or in US military subjects. Therefore, we examined whether Ad-36 infection is associated with obesity in Korean adults.
Methods:
A total of 540 age- and sex-matched individuals, who were normal weight, overweight or obese, were selected from participants in routine health examinations at the Ewha Womans University Medical Center. Overweight participants were defined as those with a body mass index (BMI) of 23⩽BMI<25 kg m
−2
and obese subjects were those with BMI⩾25 kg m
−2
, according to the International Obesity Task Force definition. Ad-36 antibody was measured using a serum neutralization assay.
Results:
Although more overweight participants than normal or obese subjects tested positive for the Ad-36 antibody (40%, 32.8% and 30%, respectively), the differences were not significant. The participants who tested positive for Ad-36 antibody had lower levels of triglycerides (TG) in each of the three groups, higher total cholesterol (TC) in the obese group and higher high-density lipoprotein-cholesterol (HDL-C) in both the normal and obese groups. The odds ratio (OR) for Ad-36 antibody positivity was greater in overweight than in normal subjects (OR=2.03; 95% confidence interval (CI), 1.16–3.55) after adjusting for age, sex and waist circumference. However, this OR was non-significant in the obese group (OR=1.56; 95% CI, 0.67–3.67).
Conclusion:
Ad-36 seems to be strongly associated with overweight, but not obese, Korean adults.</description><subject>Adenovirus diseases</subject><subject>Adenovirus Infections, Human - blood</subject><subject>Adenovirus Infections, Human - complications</subject><subject>Adenovirus Infections, Human - epidemiology</subject><subject>Adenovirus Infections, Human - immunology</subject><subject>Adenoviruses</subject><subject>Adenoviruses, Human - immunology</subject><subject>Adipocytes</subject><subject>Adult</subject><subject>Adults</subject><subject>Antibodies</subject><subject>Asian Continental Ancestry Group - statistics & numerical data</subject><subject>Biological and medical sciences</subject><subject>Biomarkers - blood</subject><subject>Body Mass Index</subject><subject>Cardiovascular disease</subject><subject>Case-Control Studies</subject><subject>Cholesterol</subject><subject>Cholesterol, HDL - blood</subject><subject>Complications and side effects</subject><subject>Cross-Sectional Studies</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Health aspects</subject><subject>Health promotion</subject><subject>Health Promotion and Disease Prevention</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Metabolic Diseases</subject><subject>Middle Aged</subject><subject>Neutralization</subject><subject>Nutrition research</subject><subject>Obesity</subject><subject>Obesity - virology</subject><subject>Odds Ratio</subject><subject>original-article</subject><subject>Overweight</subject><subject>Overweight - blood</subject><subject>Overweight - epidemiology</subject><subject>Overweight - immunology</subject><subject>Overweight - virology</subject><subject>Population</subject><subject>Prevalence</subject><subject>Public Health</subject><subject>Republic of Korea - epidemiology</subject><subject>Risk Factors</subject><subject>Task forces</subject><subject>Triglycerides - blood</subject><issn>0307-0565</issn><issn>1476-5497</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp90c2P1CAYB2BiNO64evNsGo0fBzu-0PJ1MZls_IqbeNl7AxRmmLSwQrvG_166M7qu2RgODeXhhZcfQk8xrDE04p3fxzUBjMuM3EMr3HJW01by-2gFDfAaKKMn6FHOewCgFMhDdEIwFZxAs0LvNzlH49XkY6iiq3bzqEKlehvilU9zrhtW-bJyZdMP67e7qfoak70m8zDlx-iBU0O2T47fU3Tx8cPF2ef6_NunL2eb89pQQabaEW64Zn3LtHCM9w2hRCigojVEgHG9wLR1mmhDpHPQCqF7rqUGI7ku9zxFrw9lL1P8Pts8daPPxg6DCjbOuZOlISaALfLNfyUG3IKUEuNCn_9D93FOobSx1OPlEtfoxQFt1WA7H1yckjJLzW5DBG54y8Wi1neoMno7ehODdb78v7Xh1V8bdlYN0y7HYV5iyLfh2wM0KeacrOsukx9V-lk66Zb8u5J_t-RfZqTwZ8eeZj3a_g_-HXgBL49AZaMGl1QwPt84SiVrMCuuPrhclsLWppvHufPgX4Kqwkc</recordid><startdate>20120201</startdate><enddate>20120201</enddate><creator>Na, H-N</creator><creator>Kim, J</creator><creator>Lee, H S</creator><creator>Shim, K W</creator><creator>Kimm, H</creator><creator>Jee, S H</creator><creator>Jo, I</creator><creator>Nam, J-H</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T2</scope><scope>7TK</scope><scope>7TS</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>20120201</creationdate><title>Association of human adenovirus-36 in overweight Korean adults</title><author>Na, H-N ; Kim, J ; Lee, H S ; Shim, K W ; Kimm, H ; Jee, S H ; Jo, I ; Nam, J-H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c582t-f27c7b6d46b8f67d32528a0584c280cfd8154fb2bc29ff0488bd7b9b0c97b203</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adenovirus diseases</topic><topic>Adenovirus Infections, Human - blood</topic><topic>Adenovirus Infections, Human - complications</topic><topic>Adenovirus Infections, Human - epidemiology</topic><topic>Adenovirus Infections, Human - immunology</topic><topic>Adenoviruses</topic><topic>Adenoviruses, Human - immunology</topic><topic>Adipocytes</topic><topic>Adult</topic><topic>Adults</topic><topic>Antibodies</topic><topic>Asian Continental Ancestry Group - statistics & numerical data</topic><topic>Biological and medical sciences</topic><topic>Biomarkers - blood</topic><topic>Body Mass Index</topic><topic>Cardiovascular disease</topic><topic>Case-Control Studies</topic><topic>Cholesterol</topic><topic>Cholesterol, HDL - blood</topic><topic>Complications and side effects</topic><topic>Cross-Sectional Studies</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Health aspects</topic><topic>Health promotion</topic><topic>Health Promotion and Disease Prevention</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Metabolic Diseases</topic><topic>Middle Aged</topic><topic>Neutralization</topic><topic>Nutrition research</topic><topic>Obesity</topic><topic>Obesity - virology</topic><topic>Odds Ratio</topic><topic>original-article</topic><topic>Overweight</topic><topic>Overweight - blood</topic><topic>Overweight - epidemiology</topic><topic>Overweight - immunology</topic><topic>Overweight - virology</topic><topic>Population</topic><topic>Prevalence</topic><topic>Public Health</topic><topic>Republic of Korea - epidemiology</topic><topic>Risk Factors</topic><topic>Task forces</topic><topic>Triglycerides - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Na, H-N</creatorcontrib><creatorcontrib>Kim, J</creatorcontrib><creatorcontrib>Lee, H S</creatorcontrib><creatorcontrib>Shim, K W</creatorcontrib><creatorcontrib>Kimm, H</creatorcontrib><creatorcontrib>Jee, S H</creatorcontrib><creatorcontrib>Jo, I</creatorcontrib><creatorcontrib>Nam, J-H</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Neurosciences Abstracts</collection><collection>Physical Education Index</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>International Journal of Obesity</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Na, H-N</au><au>Kim, J</au><au>Lee, H S</au><au>Shim, K W</au><au>Kimm, H</au><au>Jee, S H</au><au>Jo, I</au><au>Nam, J-H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association of human adenovirus-36 in overweight Korean adults</atitle><jtitle>International Journal of Obesity</jtitle><stitle>Int J Obes</stitle><addtitle>Int J Obes (Lond)</addtitle><date>2012-02-01</date><risdate>2012</risdate><volume>36</volume><issue>2</issue><spage>281</spage><epage>285</epage><pages>281-285</pages><issn>0307-0565</issn><eissn>1476-5497</eissn><coden>IJOBDP</coden><abstract>Background:
Although human adenovirus-36 (Ad-36) has been reported to be associated with obesity in US adults and children, Korean children and the Italian population, the association has not been found in Dutch or Belgian populations or in US military subjects. Therefore, we examined whether Ad-36 infection is associated with obesity in Korean adults.
Methods:
A total of 540 age- and sex-matched individuals, who were normal weight, overweight or obese, were selected from participants in routine health examinations at the Ewha Womans University Medical Center. Overweight participants were defined as those with a body mass index (BMI) of 23⩽BMI<25 kg m
−2
and obese subjects were those with BMI⩾25 kg m
−2
, according to the International Obesity Task Force definition. Ad-36 antibody was measured using a serum neutralization assay.
Results:
Although more overweight participants than normal or obese subjects tested positive for the Ad-36 antibody (40%, 32.8% and 30%, respectively), the differences were not significant. The participants who tested positive for Ad-36 antibody had lower levels of triglycerides (TG) in each of the three groups, higher total cholesterol (TC) in the obese group and higher high-density lipoprotein-cholesterol (HDL-C) in both the normal and obese groups. The odds ratio (OR) for Ad-36 antibody positivity was greater in overweight than in normal subjects (OR=2.03; 95% confidence interval (CI), 1.16–3.55) after adjusting for age, sex and waist circumference. However, this OR was non-significant in the obese group (OR=1.56; 95% CI, 0.67–3.67).
Conclusion:
Ad-36 seems to be strongly associated with overweight, but not obese, Korean adults.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>21587203</pmid><doi>10.1038/ijo.2011.102</doi><tpages>5</tpages></addata></record> |
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subjects | Adenovirus diseases Adenovirus Infections, Human - blood Adenovirus Infections, Human - complications Adenovirus Infections, Human - epidemiology Adenovirus Infections, Human - immunology Adenoviruses Adenoviruses, Human - immunology Adipocytes Adult Adults Antibodies Asian Continental Ancestry Group - statistics & numerical data Biological and medical sciences Biomarkers - blood Body Mass Index Cardiovascular disease Case-Control Studies Cholesterol Cholesterol, HDL - blood Complications and side effects Cross-Sectional Studies Epidemiology Female Health aspects Health promotion Health Promotion and Disease Prevention Humans Internal Medicine Male Medical sciences Medicine Medicine & Public Health Metabolic Diseases Middle Aged Neutralization Nutrition research Obesity Obesity - virology Odds Ratio original-article Overweight Overweight - blood Overweight - epidemiology Overweight - immunology Overweight - virology Population Prevalence Public Health Republic of Korea - epidemiology Risk Factors Task forces Triglycerides - blood |
title | Association of human adenovirus-36 in overweight Korean adults |
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