Lidocaine treatment during synapse reformation periods permanently inhibits NGF-induced excitation in an identified reconstructed synapse of Lymnaea stagnalis

Purpose Nerve growth factor (NGF) has been reported to affect synaptic transmission and cause neuropathic pain. In contrast, lidocaine has been used to reduce neuropathic pain; however, the effect of NGF and lidocaine on spontaneous transmitter release and synapse excitation has not been fully defin...

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Veröffentlicht in:Journal of anesthesia 2012-02, Vol.26 (1), p.45-53
Hauptverfasser: Onizuka, Shin, Shiraishi, Seiji, Tamura, Ryuuji, Yonaha, Tetsu, Oda, Nobuko, Kawasaki, Yuko, Syed, Naweed I., Shirasaka, Tetsuro, Tsuneyoshi, Isao
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Sprache:eng
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