Identification of differentially expressed proteins in the spinal cord of neuropathic pain models with PKCgamma silence by proteomic analysis

Abstract In order to elucidate the mechanisms that PKCγ regulates neuropathic pain (NP), and detect proteins that are associated with the function of PKCγ in NP, we exploited a chronic constriction injury (CCI)-induced neuropathic pain rat (CCI-NP rat) model in which PKCγ knockdown in the spinal cor...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain research 2012-02, Vol.1440, p.34-46
Hauptverfasser:	Zou, Wangyuan, Zhan, Xianquan, Li, Maoyu, Song, Zongbin, Liu, Chang, Peng, Fang, Guo, Qulian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - metabolism Aldehyde Reductase - metabolism Animals antioxidants brain computer software Constriction, Pathologic cytoskeleton Electrophoresis, Gel, Two-Dimensional gels heat shock proteins homeostasis Immunohistochemistry Male mass spectrometry Neuralgia - metabolism Neurology Neuropathic pain pain PKCγ Protein Kinase C - genetics Protein Kinase C - metabolism protein synthesis Proteins - metabolism Proteomics Rats Rats, Sprague-Dawley RNA Interference Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Spinal spinal cord Spinal Cord - metabolism Synaptosomal-Associated Protein 25 - metabolism two-dimensional gel electrophoresis Western blotting
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!