Piceatannol inhibits migration and invasion of prostate cancer cells: possible mediation by decreased interleukin-6 signaling

Piceatannol (trans-3,4,3′,5′-tetrahydroxystilbene) is a polyphenol detected in grapes, red wine and Rheum undulatum; it has also been demonstrated to exert anticarcinogenic effects. In this study, in order to determine whether piceatannol inhibits the lung metastasis of prostate cancer cells, MAT-Ly...

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Veröffentlicht in:	The Journal of nutritional biochemistry 2012-03, Vol.23 (3), p.228-238
Hauptverfasser:	Kwon, Gyoo Taik, Jung, Jae In, Song, Hye Rim, Woo, Eun Young, Jun, Jong-Gab, Kim, Jin-Kyung, Her, Song, Park, Jung Han Yoon
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Line, Tumor Epidermal Growth Factor - drug effects Epidermal Growth Factor - metabolism Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Gene Expression Regulation Humans Interleukin-6 Interleukin-6 - antagonists & inhibitors Interleukin-6 - metabolism Interleukin-6 - secretion Male Matrix metalloproteinase Matrix Metalloproteinase 9 - genetics Matrix Metalloproteinase 9 - metabolism Mice Mice, Inbred BALB C Neoplasm Metastasis - drug therapy Neoplasm Metastasis - pathology Phosphorylation Piceatannol Prostate cancer cells Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Rheum Signal Transduction - drug effects STAT3 STAT3 Transcription Factor - genetics STAT3 Transcription Factor - metabolism Stilbenes - pharmacology Urokinase-Type Plasminogen Activator - genetics Urokinase-Type Plasminogen Activator - metabolism Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - metabolism Vertebrates: anatomy and physiology, studies on body, several organs or systems Vitaceae
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