In vitro evaluation of powders for inhalation: The effect of drug concentration on particle detachment

Limited information on the effect of the drug concentration on the performance of powders for inhalation is currently published. The aim of this work was to study the influence of drug concentration on the adhesion between drug and carrier and on the drug detachment from the carrier. The study was d...

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Veröffentlicht in:	International journal of pharmaceutics 2012-03, Vol.424 (1-2), p.44-49
Hauptverfasser:	Le, V.N.P., Hoang Thi, T.H., Robins, E., Flament, M.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion Adhesiveness Aerodynamic behaviour air Androstadienes - chemistry breathing Bronchodilator Agents - chemistry Chemistry, Pharmaceutical Concentration drug carriers Drug Carriers - chemistry drugs Dry powder inhaler Dry Powder Inhalers Ethanolamines - chemistry Fluticasone Fluticasone propionate Formoterol Fumarate in vitro studies lactose Lactose - chemistry physicochemical properties Powders propionic acid sieving
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