Pancreatic ductal adenocarcinoma in hereditary diffuse gastric cancer. A case report

Summary Hereditary diffuse gastric cancer is an autosomal dominant cancer syndrome characterized by highly penetrant diffuse gastric cancer. It is caused by germ line mutations in CDH1 , encoding the cell-cell adhesion protein E-cadherin. Pancreatic ductal adenocarcinoma is one of the most dismal ma...

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Veröffentlicht in:	Human pathology 2012-03, Vol.43 (3), p.457-461
Hauptverfasser:	Ottenhof, Niki A., MSc, de Wilde, Roeland F., MD, Morsink, Folkert H.M., BSc, de Leng, Wendy W.J., PhD, Ausems, Margreet G.E.M., MD, PhD, Morreau, Hans, MD, PhD, van Hillegersberg, Richard, MD, Offerhaus, G. Johan A., MD, PhD, Milne, Anya N., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma - metabolism Adenocarcinoma - pathology Biological and medical sciences Cadherins - genetics Cadherins - metabolism Carcinoma, Pancreatic Ductal - genetics Carcinoma, Pancreatic Ductal - metabolism Carcinoma, Pancreatic Ductal - pathology CDH-1 DNA Mutational Analysis E-cadherin Fatal Outcome Gastrectomy Gastroenterology. Liver. Pancreas. Abdomen Germ-Line Mutation Hereditary diffuse gastric cancer Humans Investigative techniques, diagnostic techniques (general aspects) Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Middle Aged Neoplasm Recurrence, Local Neoplasms, Multiple Primary Pancreatic ductal adenocarcinoma Pancreatic Neoplasms - genetics Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - pathology Pathology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Polymorphism, Single Nucleotide Proteomics Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins p21(ras) ras Proteins - genetics ras Proteins - metabolism Stomach Neoplasms - genetics Stomach Neoplasms - metabolism Stomach Neoplasms - pathology Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - metabolism Tumors
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