$Assessment of anxiolytic and panicolytic effects of dichloromethane fraction from stems of Kielmeyera coriacea$

Assessment of anxiolytic and panicolytic effects of dichloromethane fraction from stems of Kielmeyera coriacea

Kielmeyera coriacea Mart. (Calophyllaceae) is known popularly as “Pau Santo”. The hydroethanolic extract (HE) of Kielmeyera coriacea stems and its semi-pure dichloromethane (DCM) constituent produced an antidepressant-like effect in rats. The purpose of this study was to investigate the effects of r...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2012-02, Vol.19 (3-4), p.374-377
Hauptverfasser:	Biesdorf, C., Cortez, D.A.G., Audi, E.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	1,3,7-Trihydroxy-2-(3-methylbut-2-enyl)-xanthone Animals Anti-Anxiety Agents - pharmacology Antidepressive Agents, Tricyclic - administration & dosage Antidepressive Agents, Tricyclic - pharmacology Anxiety - drug therapy Behavior, Animal Chemical properties Clusiaceae - chemistry Dicotyledons Elevated T-maze Exploratory Behavior Generalized anxiety disorder Health aspects Imipramine - pharmacology Kielmeyera coriacea Male Materia medica, Vegetable Maze Learning - drug effects Methylene chloride Methylene Chloride - administration & dosage Methylene Chloride - chemistry Methylene Chloride - pharmacology Motor Activity Panic disorder Panic Disorder - drug therapy Plant extracts Plant Extracts - chemistry Plant Extracts - pharmacology Plant Stems - chemistry Rats Rats, Wistar Xanthones - chemistry Xanthones - pharmacology
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