Antenatal Thyroid Screening and Childhood Cognitive Function

In this randomized trial, antenatal screening (at a median gestational age of 12 weeks 3 days) and treatment for hypothyroidism did not result in improved cognitive function in children at 3 years of age. Active secretion of thyroid hormone in the fetus does not start until about 18 to 20 weeks'...

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Veröffentlicht in:	The New England journal of medicine 2012-02, Vol.366 (6), p.493-501
Hauptverfasser:	Lazarus, John H, Bestwick, Jonathan P, Channon, Sue, Paradice, Ruth, Maina, Aldo, Rees, Rhian, Chiusano, Elisabetta, John, Rhys, Guaraldo, Varvara, George, Lynne M, Perona, Marco, Dall'Amico, Daniela, Parkes, Arthur B, Joomun, Mohammed, Wald, Nicholas J
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Child, Preschool Children Cognitive ability Female Fetuses Gestational Age Humans Hypothyroidism Hypothyroidism - diagnosis Hypothyroidism - drug therapy Intellectual Disability - diagnosis Intellectual Disability - etiology Intelligence Intelligence Tests Intention to Treat Analysis Male Medical screening Motivation Pregnancy Pregnancy Complications - diagnosis Pregnancy Complications - drug therapy Pregnancy Trimester, Second - blood Prenatal Diagnosis Prenatal Exposure Delayed Effects - diagnosis Thyroid Thyroid diseases Thyroid gland Thyroid Hormones - metabolism Thyroid-stimulating hormone Thyrotropin - blood Thyroxine Thyroxine - blood Thyroxine - therapeutic use
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