Developing a new clinical tool for diagnosing chronic Q fever: the Coxiella ELISPOT

Abstract Definitively establishing a clinical diagnosis of chronic Q fever remains challenging, as the diagnostic performance of both conventional serological tests and PCR is limited. Given the importance of an early diagnosis of chronic Q fever, there is a need for a reliable diagnostic test. We d...

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Veröffentlicht in:	FEMS immunology and medical microbiology 2012-02, Vol.64 (1), p.57-60
Hauptverfasser:	Limonard, Gijs J.M., Thijsen, Steven F., Bossink, Aik W., Asscheman, Anita, Bouwman, John J.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antigens Antigens, Bacterial Bacterial diseases Bacteriology Biological and medical sciences Chronic illnesses Clinical Laboratory Techniques - methods Coxiella burnetii Coxiella burnetii - immunology Diagnosis Diagnostic systems ELISPOT Enzyme-linked immunosorbent assay Enzyme-Linked Immunospot Assay - methods Female Fundamental and applied biological sciences. Psychology gamma -Interferon Health risk assessment Human bacterial diseases Humans Infectious diseases Interferon Interferon-gamma - secretion Lymphocytes T Male Medical sciences Microbiology Middle Aged Miscellaneous Polymerase chain reaction Q fever Q Fever - diagnosis Rickettsial diseases Serological tests T-Lymphocytes - immunology Tropical bacterial diseases γ-Interferon
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