Real-time PCR versus viral culture on urine as a gold standard in the diagnosis of congenital cytomegalovirus infection

Abstract Background Cytomegalovirus (CMV) infection is the most common cause of congenital infection. Whereas CMV PCR has replaced viral culture and antigen detection in immunocompromised patients because of higher sensitivity, viral culture of neonatal urine is still referred to as the gold standar...

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Veröffentlicht in:	Journal of clinical virology 2012-02, Vol.53 (2), p.167-170
Hauptverfasser:	de Vries, Jutte J.C, van der Eijk, Annemiek A, Wolthers, Katja C, Rusman, Lisette G, Pas, Suzan D, Molenkamp, Richard, Claas, Eric C, Kroes, Aloys C.M, Vossen, Ann C.T.M
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Biological and medical sciences Congenital CMV Culture Cytomegalovirus Cytomegalovirus - genetics Cytomegalovirus - isolation & purification Cytomegalovirus Infections - congenital Cytomegalovirus Infections - diagnosis Cytomegalovirus Infections - virology Female Fundamental and applied biological sciences. Psychology Human viral diseases Humans Infant, Newborn Infectious Disease Infectious diseases Male Medical sciences Microbiology Miscellaneous PCR Real-Time Polymerase Chain Reaction - standards Sensitivity Sensitivity and Specificity Urine - virology Viral diseases Virology Virus Cultivation - standards
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