Elucidating the mechanism of regulation of TGF- type II receptor expression in human lung cancer cell lines

Lung carcinogenesis in humans involves an accumulation of genetic and epigenetic changes that lead to alterations in normal lung epithelium, to in situ carcinoma, and finally to invasive and metastatic cancers. The loss of TGF--induced tumor suppressor function in tumors plays a pivotal role in this...

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Veröffentlicht in:Neoplasia (New York, N.Y.) N.Y.), 2011-10, Vol.13 (10)
Hauptverfasser: Halder, S K, Cho, Y-J, Datta, A, Anumanthan, G, Ham, A-JL, Carbone, D P, Datta, P K
Format: Artikel
Sprache:eng
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