The relationship between motor planning and freezing of gait in Parkinson's disease
ObjectiveTo examine how a cued change in motor plan influences Parkinson's disease (PD) patients with freezing of gait (FOG) (PD FOG; n=10), compared with those without FOG (PD non-FOG; n=10) and healthy controls (n=10).MethodsParticipants walked through a doorway in three experimental conditio...
Gespeichert in:
| Veröffentlicht in: | Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2012-01, Vol.83 (1), p.98-101 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 101 |
|---|---|
| container_issue | 1 |
| container_start_page | 98 |
| container_title | Journal of neurology, neurosurgery and psychiatry |
| container_volume | 83 |
| creator | Knobl, Patricia Kielstra, Lauren Almeida, Quincy |
| description | ObjectiveTo examine how a cued change in motor plan influences Parkinson's disease (PD) patients with freezing of gait (FOG) (PD FOG; n=10), compared with those without FOG (PD non-FOG; n=10) and healthy controls (n=10).MethodsParticipants walked through a doorway in three experimental conditions: no cue; cue before gait initiation; and cue after gait initiation. The light cue was presented at the end of the pathway and signified that individuals must walk to the cue, turn around and return to starting position.ResultsStep-to-step variability (a known precursor to FOG) revealed a significant main effect of group (F2,27=32.83, p |
| doi_str_mv | 10.1136/jnnp-2011-300869 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_920805333</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>911944391</sourcerecordid><originalsourceid>FETCH-LOGICAL-b528t-7a107b50f714bbb69b77b737418fd5d616d7dbc2a576d4d239a278eb3e29266c3</originalsourceid><addsrcrecordid>eNqFkU1v1DAQhi1ERZfCnROyhFAPKOCxYzs-Vis-qlZAYam4WXbitF4SJ9hZ8fHr65ClSFzqi2XNM6_G8yD0BMhLACZebUMYC0oACkZIJdQ9tIJSVAVj5Ot9tCKE0lzh5BA9TGlL5lOpB-iQQsUEYbBCnzfXDkfXmckPIV37EVs3_XAu4H6YhojHzoTgwxU2ocFtdO73_BhafGX8hH3AH0385kMawnHCjU_OJPcIHbSmS-7x_j5CX9683qzfFecf3p6uT84Ly2k1FdIAkZaTVkJprRXKSmklkyVUbcMbAaKRja2p4VI0ZUOZMlRWzjJHFRWiZkfoeMkd4_B959Kke59q1-WR3bBLWlFSEc7yuZMEUGXJFGTy2X_kdtjFkL-hQVZASwF8ziMLVcchpehaPUbfm_hLA9GzGT2b0bMZvZjJLU_3wTvbu-a24a-KDDzfAybVpmujCbVP_7i8M8X_BBUL59Pkft7WswYt8va4fn-51vwCLs8-bZS-yPyLhbf99u4xbwC3RbIe</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1781246153</pqid></control><display><type>article</type><title>The relationship between motor planning and freezing of gait in Parkinson's disease</title><source>MEDLINE</source><source>BMJ Journals - NESLi2</source><creator>Knobl, Patricia ; Kielstra, Lauren ; Almeida, Quincy</creator><creatorcontrib>Knobl, Patricia ; Kielstra, Lauren ; Almeida, Quincy</creatorcontrib><description>ObjectiveTo examine how a cued change in motor plan influences Parkinson's disease (PD) patients with freezing of gait (FOG) (PD FOG; n=10), compared with those without FOG (PD non-FOG; n=10) and healthy controls (n=10).MethodsParticipants walked through a doorway in three experimental conditions: no cue; cue before gait initiation; and cue after gait initiation. The light cue was presented at the end of the pathway and signified that individuals must walk to the cue, turn around and return to starting position.ResultsStep-to-step variability (a known precursor to FOG) revealed a significant main effect of group (F2,27=32.83, p<0.001), where PD FOG walked with greater step length variability than PD non-FOG and the control group. A significant interaction (F4,54=3.035, p=0.025) demonstrated that only the PD FOG group was most variable when the cue was present before gait initiation.ConclusionThis study concludes that motor planning deficits affect gait, specifically in individuals who experience FOG. This may have important implications for the design of therapeutic interventions in PD FOG.</description><identifier>ISSN: 0022-3050</identifier><identifier>EISSN: 1468-330X</identifier><identifier>DOI: 10.1136/jnnp-2011-300869</identifier><identifier>PMID: 21836031</identifier><identifier>CODEN: JNNPAU</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd</publisher><subject>Aged ; Aged, 80 and over ; apraxia ; bimanual coordination ; Biological and medical sciences ; Case-Control Studies ; cognition ; Cues ; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases ; Executive function ; Female ; freezing ; Gait ; Gait - physiology ; Humans ; Light ; Male ; Medical sciences ; Middle Aged ; motor plan ; Movement - physiology ; Neurology ; Parkinson Disease - physiopathology ; Parkinson's disease ; Planning ; proprioception ; Walking</subject><ispartof>Journal of neurology, neurosurgery and psychiatry, 2012-01, Vol.83 (1), p.98-101</ispartof><rights>2011, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright: 2011 (c) 2011, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b528t-7a107b50f714bbb69b77b737418fd5d616d7dbc2a576d4d239a278eb3e29266c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://jnnp.bmj.com/content/83/1/98.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttps://jnnp.bmj.com/content/83/1/98.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,314,776,780,3183,23550,27901,27902,77343,77374</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25289569$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21836031$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Knobl, Patricia</creatorcontrib><creatorcontrib>Kielstra, Lauren</creatorcontrib><creatorcontrib>Almeida, Quincy</creatorcontrib><title>The relationship between motor planning and freezing of gait in Parkinson's disease</title><title>Journal of neurology, neurosurgery and psychiatry</title><addtitle>J Neurol Neurosurg Psychiatry</addtitle><description>ObjectiveTo examine how a cued change in motor plan influences Parkinson's disease (PD) patients with freezing of gait (FOG) (PD FOG; n=10), compared with those without FOG (PD non-FOG; n=10) and healthy controls (n=10).MethodsParticipants walked through a doorway in three experimental conditions: no cue; cue before gait initiation; and cue after gait initiation. The light cue was presented at the end of the pathway and signified that individuals must walk to the cue, turn around and return to starting position.ResultsStep-to-step variability (a known precursor to FOG) revealed a significant main effect of group (F2,27=32.83, p<0.001), where PD FOG walked with greater step length variability than PD non-FOG and the control group. A significant interaction (F4,54=3.035, p=0.025) demonstrated that only the PD FOG group was most variable when the cue was present before gait initiation.ConclusionThis study concludes that motor planning deficits affect gait, specifically in individuals who experience FOG. This may have important implications for the design of therapeutic interventions in PD FOG.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>apraxia</subject><subject>bimanual coordination</subject><subject>Biological and medical sciences</subject><subject>Case-Control Studies</subject><subject>cognition</subject><subject>Cues</subject><subject>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</subject><subject>Executive function</subject><subject>Female</subject><subject>freezing</subject><subject>Gait</subject><subject>Gait - physiology</subject><subject>Humans</subject><subject>Light</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>motor plan</subject><subject>Movement - physiology</subject><subject>Neurology</subject><subject>Parkinson Disease - physiopathology</subject><subject>Parkinson's disease</subject><subject>Planning</subject><subject>proprioception</subject><subject>Walking</subject><issn>0022-3050</issn><issn>1468-330X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkU1v1DAQhi1ERZfCnROyhFAPKOCxYzs-Vis-qlZAYam4WXbitF4SJ9hZ8fHr65ClSFzqi2XNM6_G8yD0BMhLACZebUMYC0oACkZIJdQ9tIJSVAVj5Ot9tCKE0lzh5BA9TGlL5lOpB-iQQsUEYbBCnzfXDkfXmckPIV37EVs3_XAu4H6YhojHzoTgwxU2ocFtdO73_BhafGX8hH3AH0385kMawnHCjU_OJPcIHbSmS-7x_j5CX9683qzfFecf3p6uT84Ly2k1FdIAkZaTVkJprRXKSmklkyVUbcMbAaKRja2p4VI0ZUOZMlRWzjJHFRWiZkfoeMkd4_B959Kke59q1-WR3bBLWlFSEc7yuZMEUGXJFGTy2X_kdtjFkL-hQVZASwF8ziMLVcchpehaPUbfm_hLA9GzGT2b0bMZvZjJLU_3wTvbu-a24a-KDDzfAybVpmujCbVP_7i8M8X_BBUL59Pkft7WswYt8va4fn-51vwCLs8-bZS-yPyLhbf99u4xbwC3RbIe</recordid><startdate>20120101</startdate><enddate>20120101</enddate><creator>Knobl, Patricia</creator><creator>Kielstra, Lauren</creator><creator>Almeida, Quincy</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>7TK</scope></search><sort><creationdate>20120101</creationdate><title>The relationship between motor planning and freezing of gait in Parkinson's disease</title><author>Knobl, Patricia ; Kielstra, Lauren ; Almeida, Quincy</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b528t-7a107b50f714bbb69b77b737418fd5d616d7dbc2a576d4d239a278eb3e29266c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>apraxia</topic><topic>bimanual coordination</topic><topic>Biological and medical sciences</topic><topic>Case-Control Studies</topic><topic>cognition</topic><topic>Cues</topic><topic>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</topic><topic>Executive function</topic><topic>Female</topic><topic>freezing</topic><topic>Gait</topic><topic>Gait - physiology</topic><topic>Humans</topic><topic>Light</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>motor plan</topic><topic>Movement - physiology</topic><topic>Neurology</topic><topic>Parkinson Disease - physiopathology</topic><topic>Parkinson's disease</topic><topic>Planning</topic><topic>proprioception</topic><topic>Walking</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Knobl, Patricia</creatorcontrib><creatorcontrib>Kielstra, Lauren</creatorcontrib><creatorcontrib>Almeida, Quincy</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><jtitle>Journal of neurology, neurosurgery and psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Knobl, Patricia</au><au>Kielstra, Lauren</au><au>Almeida, Quincy</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The relationship between motor planning and freezing of gait in Parkinson's disease</atitle><jtitle>Journal of neurology, neurosurgery and psychiatry</jtitle><addtitle>J Neurol Neurosurg Psychiatry</addtitle><date>2012-01-01</date><risdate>2012</risdate><volume>83</volume><issue>1</issue><spage>98</spage><epage>101</epage><pages>98-101</pages><issn>0022-3050</issn><eissn>1468-330X</eissn><coden>JNNPAU</coden><abstract>ObjectiveTo examine how a cued change in motor plan influences Parkinson's disease (PD) patients with freezing of gait (FOG) (PD FOG; n=10), compared with those without FOG (PD non-FOG; n=10) and healthy controls (n=10).MethodsParticipants walked through a doorway in three experimental conditions: no cue; cue before gait initiation; and cue after gait initiation. The light cue was presented at the end of the pathway and signified that individuals must walk to the cue, turn around and return to starting position.ResultsStep-to-step variability (a known precursor to FOG) revealed a significant main effect of group (F2,27=32.83, p<0.001), where PD FOG walked with greater step length variability than PD non-FOG and the control group. A significant interaction (F4,54=3.035, p=0.025) demonstrated that only the PD FOG group was most variable when the cue was present before gait initiation.ConclusionThis study concludes that motor planning deficits affect gait, specifically in individuals who experience FOG. This may have important implications for the design of therapeutic interventions in PD FOG.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd</pub><pmid>21836031</pmid><doi>10.1136/jnnp-2011-300869</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3050 |
| ispartof | Journal of neurology, neurosurgery and psychiatry, 2012-01, Vol.83 (1), p.98-101 |
| issn | 0022-3050 1468-330X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_920805333 |
| source | MEDLINE; BMJ Journals - NESLi2 |
| subjects | Aged Aged, 80 and over apraxia bimanual coordination Biological and medical sciences Case-Control Studies cognition Cues Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Executive function Female freezing Gait Gait - physiology Humans Light Male Medical sciences Middle Aged motor plan Movement - physiology Neurology Parkinson Disease - physiopathology Parkinson's disease Planning proprioception Walking |
| title | The relationship between motor planning and freezing of gait in Parkinson's disease |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T06%3A08%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20relationship%20between%20motor%20planning%20and%20freezing%20of%20gait%20in%20Parkinson's%20disease&rft.jtitle=Journal%20of%20neurology,%20neurosurgery%20and%20psychiatry&rft.au=Knobl,%20Patricia&rft.date=2012-01-01&rft.volume=83&rft.issue=1&rft.spage=98&rft.epage=101&rft.pages=98-101&rft.issn=0022-3050&rft.eissn=1468-330X&rft.coden=JNNPAU&rft_id=info:doi/10.1136/jnnp-2011-300869&rft_dat=%3Cproquest_cross%3E911944391%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1781246153&rft_id=info:pmid/21836031&rfr_iscdi=true |