Radioprotective effect of Ocimum sanctum and amifostine on the salivary gland of rats after therapeutic radioiodine exposure

The current study investigated the radioprotective effect of Ocimum sanctum on the salivary gland of rats administered radioiodine ((131)I) and compared its efficacy with a known radioprotectant, amifostine. The experimental rats were divided in four groups and sacrificed in three different batches...

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Veröffentlicht in:	Cancer biotherapy & radiopharmaceuticals 2011-12, Vol.26 (6), p.737-743
Hauptverfasser:	Joseph, Lebana J, Bhartiya, Uma S, Raut, Yogita S, Hawaldar, Rohini W, Nayak, Yogendra, Pawar, Yogita P, Jambhekar, Nirmala A, Rajan, M G R
Format:	Artikel
Sprache:	eng
Schlagworte:	Amifostine - pharmacokinetics Amifostine - pharmacology Animals Female Iodine Radioisotopes - pharmacology Ocimum - chemistry Ocimum sanctum Parotid Gland - drug effects Parotid Gland - metabolism Parotid Gland - pathology Parotid Gland - radiation effects Phytotherapy - methods Plant Preparations - pharmacokinetics Plant Preparations - pharmacology Radiation-Protective Agents - pharmacokinetics Radiation-Protective Agents - pharmacology Radiopharmaceuticals - pharmacokinetics Radiopharmaceuticals - pharmacology Radiotherapy - methods Rats Rats, Wistar Sodium Pertechnetate Tc 99m - pharmacokinetics Sodium Pertechnetate Tc 99m - pharmacology Tissue Distribution
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