Why are hippocampal CA1 neurons vulnerable but motor cortex neurons resistant to transient ischemia?

J. Neurochem. (2012) 120, 574–585. It is well‐known that heat‐shock protein 70.1 (Hsp70.1), a major protein of the human Hsp70 family, plays cytoprotective roles by both its chaperone function and stabilization of lysosomal membranes. Recently, we found that calpain‐mediated cleavage of carbonylated...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neurochemistry 2012-02, Vol.120 (4), p.574-585
Hauptverfasser:	Zhu, Hong, Yoshimoto, Tanihiro, Imajo-Ohmi, Shinobu, Dazortsava, Maryia, Mathivanan, Arumugam, Yamashima, Tetsumori
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Biological and medical sciences Brain CA1 Region, Hippocampal - blood supply CA1 Region, Hippocampal - metabolism CA1 Region, Hippocampal - pathology Calpain Cardiology. Vascular system cathepsin Cell Death - physiology Cell survival cerebral ischemia Chaperones Cornus Cortex (motor) Heat shock proteins Hippocampus HSP70 Heat-Shock Proteins - physiology Hsp70 protein Hsp70.1 Ischemia Ischemic Attack, Transient - metabolism Ischemic Attack, Transient - pathology Macaca Medical sciences Motor Cortex - blood supply Motor Cortex - metabolism Motor Cortex - pathology Neurochemistry Neurology neuronal death Neurons Neurons - metabolism Neurons - pathology Neuroprotection NF- Kappa B protein NF-κB Protein Binding - physiology Reperfusion Vascular diseases and vascular malformations of the nervous system
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!