Emergence of a Neisseria gonorrhoeae clone showing decreased susceptibility to cefixime in England and Wales

Objectives The third-generation cephalosporins recommended in national guidelines are amongst the last remaining effective agents for treatment of gonorrhoea. This study characterizes gonococcal isolates with decreased cefixime susceptibility from England and Wales. Methods A total of 96 isolates of...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2011-11, Vol.66 (11), p.2509-2512
Hauptverfasser:	Chisholm, Stephanie A., Alexander, Sarah, Desouza-Thomas, Leah, Maclure-Webster, Elisabeth, Anderson, John, Nichols, Tom, Lowndes, Catherine M., Ison, Catherine A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Antibiotics. Antiinfectious agents. Antiparasitic agents Antimicrobial agents Bacterial diseases Bacterial diseases of the genital system Biological and medical sciences Cefixime - pharmacology Ciprofloxacin - pharmacology Drug resistance Drug Resistance, Multiple, Bacterial - genetics Drug therapy England - epidemiology Epidemiology. Vaccinations Female General aspects Gonorrhea - drug therapy Gonorrhea - epidemiology Gonorrhea - microbiology Gram-negative bacteria Human bacterial diseases Humans Infectious diseases Male Medical sciences Microbial Sensitivity Tests Middle Aged Molecular Epidemiology Molecular Typing Neisseria gonorrhoeae Neisseria gonorrhoeae - drug effects Neisseria gonorrhoeae - genetics Neisseria gonorrhoeae - isolation & purification Penicillin Penicillins - pharmacology Pharmacology. Drug treatments Sexual Behavior Tetracycline - pharmacology Wales
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