Use of human hepatocyte-like cells derived from induced pluripotent stem cells as a model for hepatocytes in hepatitis C virus infection

► HCV pseudo-particles infected iPS-derived hepatocyte-like cells. ► HCV subgenomic RNA replicated in iPS-derived hepatocyte-like cells. ► A known inhibitor of HCV infection attenuated HCV infection in iPS-derived hepatocyte-like cells. ► A known inhibitor of HCV replication attenuated replication o...

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Veröffentlicht in:	Biochemical and biophysical research communications 2011-12, Vol.416 (1), p.119-124
Hauptverfasser:	Yoshida, Takeshi, Takayama, Kazuo, Kondoh, Masuo, Sakurai, Fuminori, Tani, Hideki, Sakamoto, Naoya, Matsuura, Yoshiharu, Mizuguchi, Hiroyuki, Yagi, Kiyohito
Format:	Artikel
Sprache:	eng
Schlagworte:	Experimental model Hepacivirus - physiology Hepatitis C Hepatitis C virus Hepatocyte Hepatocytes - virology Humans Induced pluripotent stem cell Infection Models, Biological Pan troglodytes Pluripotent Stem Cells - cytology Replication Virus Internalization Virus Replication
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