Low frequency stimulation of ventral hippocampal commissures reduces seizures in a rat model of chronic temporal lobe epilepsy

Summary Purpose: To investigate the effects of low frequency stimulation (LFS) of a fiber tract for the suppression of spontaneous seizures in a rat model of human temporal lobe epilepsy. Methods: Stimulation electrodes were implanted into the ventral hippocampal commissure (VHC) in a rat post‐sta...

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Veröffentlicht in:	Epilepsia (Copenhagen) 2012-01, Vol.53 (1), p.147-156
Hauptverfasser:	Rashid, Saifur, Pho, Gerald, Czigler, Michael, Werz, Mary A., Durand, Dominique M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amygdala Animal models Animals Anticonvulsants. Antiepileptics. Antiparkinson agents Biological and medical sciences Brain stimulation CA3 Region, Hippocampal - physiopathology Data processing Deep brain stimulation Disease Models, Animal Electric Stimulation - methods Electric Stimulation Therapy - methods Electrodes Electrodes, Implanted Electroencephalography Epilepsy Epilepsy, Temporal Lobe - physiopathology Epilepsy, Temporal Lobe - therapy Excitability Fibers Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Hemorrhage Hippocampus Low frequency stimulation Male Medical sciences Nervous system (semeiology, syndromes) Neurology Neuropharmacology Pharmacology. Drug treatments Rats Rats, Sprague-Dawley Seizures Seizures - physiopathology Seizures - therapy Temporal lobe Temporal lobe epilepsy Treatment Outcome Ventral hippocampal commissure Waves
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