Liver-specific mitochondrial respiratory chain complex I deficiency in fatal influenza encephalopathy

Abstract We report on a 4-year-old boy who died from influenza encephalopathy. The clinical course and microscopic findings of the autopsied liver were compatible with Reye’s syndrome. We examined the mitochondrial respiratory chain function by blue native polyacrylamide gel electrophoresis (BN-PAGE...

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Veröffentlicht in:	Brain & development (Tokyo. 1979) 2012-02, Vol.34 (2), p.115-117
Hauptverfasser:	Arakawa, Chikako, Endo, Ayumi, Kohira, Ryutaro, Fujita, Yukihiko, Fuchigami, Tatsuo, Mugishima, Hideo, Ohtake, Akira, Murayama, Kei, Mori, Masato, Miyata, Rie, Hatai, Yoshiho
Format:	Artikel
Sprache:	eng
Schlagworte:	Child, Preschool Complex I deficiency Electron Transport Complex I - deficiency Electron Transport Complex I - metabolism Electron Transport Complex IV - metabolism Encephalitis Viruses - pathogenicity Humans Influenza encephalopathy Influenza, Human - complications Liver - enzymology Liver-specific Male Mitochondria Mitochondrial Diseases - complications Mitochondrial Diseases - metabolism Mitochondrial Diseases - pathology Neurology Reye’s syndrome
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