TAZ is required for the osteogenic and anti-adipogenic activities of kaempferol

Abstract Kaempferol (KMP) exerts protective effects against both osteoporosis and obesity by regulating cellular activities, but the underlying molecular mechanisms have not been fully elucidated. TAZ (transcriptional coactivator with PDZ-binding motif) modulates both osteoblast and adipocyte differ...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2012-01, Vol.50 (1), p.364-372
Hauptverfasser:	Byun, Mi Ran, Jeong, Hana, Bae, Su Jung, Kim, A Rum, Hwang, Eun Sook, Hong, Jeong-Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipogenesis - drug effects Animals Biological and medical sciences Cell Differentiation - drug effects Cell Line Core Binding Factor Alpha 1 Subunit - genetics Core Binding Factor Alpha 1 Subunit - metabolism Fundamental and applied biological sciences. Psychology Humans Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Kaempferols - pharmacology Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - drug effects Mesenchymal Stromal Cells - physiology Mice Mice, Knockout Orthopedics Osteoblasts - cytology Osteoblasts - drug effects Osteoblasts - physiology Osteogenesis - drug effects PPAR gamma - genetics PPAR gamma - metabolism Transcriptional Activation Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!