Risk factors for surgical site infection after elective resection for rectal cancer. A multivariate analysis on 2131 patients
Aim Surgical site infection (SSI) is the most common cause of morbidity after colorectal surgery. The aim of this study was to analyze risk factors for SSI in patients who had undergone surgery for rectal cancer. Method A multicentre observational study was carried out on 2131 patients operated on...
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| Veröffentlicht in: | Colorectal disease 2012-03, Vol.14 (3), p.e95-e102 |
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| creator | Biondo, S. Kreisler, E. Fraccalvieri, D. Basany, E. E. Codina-Cazador, A. Ortiz, H. |
| description | Aim Surgical site infection (SSI) is the most common cause of morbidity after colorectal surgery. The aim of this study was to analyze risk factors for SSI in patients who had undergone surgery for rectal cancer.
Method A multicentre observational study was carried out on 2131 patients operated on for rectal cancer between May 2006 and May 2009. Twenty‐nine centres were involved. SSI included wound infection and organ space infection within 30 days after the operation. Univariate and multivariate analyses were carried out to study possible risk factors for SSI.
Results Wound infection and organ space infection were diagnosed in 8.9% and 10%, respectively, of patients. The anastomotic leakage rate was 8%. Multivariate analysis showed that wound infection was related to tumour stage, a converted laparoscopic procedure and open surgery. Organ space infection was related to Stage IV tumour, a tumour < 11 cm from the anal verge, low anterior resection and Hartmann’s procedure.
Conclusion Rectal surgery for malignant disease is associated with a considerable rate of SSI. Wound infection and organ space infection are related to different factors and therefore should be evaluated separately. |
| doi_str_mv | 10.1111/j.1463-1318.2011.02798.x |
| format | Article |
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Method A multicentre observational study was carried out on 2131 patients operated on for rectal cancer between May 2006 and May 2009. Twenty‐nine centres were involved. SSI included wound infection and organ space infection within 30 days after the operation. Univariate and multivariate analyses were carried out to study possible risk factors for SSI.
Results Wound infection and organ space infection were diagnosed in 8.9% and 10%, respectively, of patients. The anastomotic leakage rate was 8%. Multivariate analysis showed that wound infection was related to tumour stage, a converted laparoscopic procedure and open surgery. Organ space infection was related to Stage IV tumour, a tumour < 11 cm from the anal verge, low anterior resection and Hartmann’s procedure.
Conclusion Rectal surgery for malignant disease is associated with a considerable rate of SSI. Wound infection and organ space infection are related to different factors and therefore should be evaluated separately.</description><identifier>ISSN: 1462-8910</identifier><identifier>EISSN: 1463-1318</identifier><identifier>DOI: 10.1111/j.1463-1318.2011.02798.x</identifier><identifier>PMID: 21883813</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adenocarcinoma - mortality ; Adenocarcinoma - pathology ; Adenocarcinoma - surgery ; Adult ; Aged ; Aged, 80 and over ; Anastomotic Leak - epidemiology ; Anastomotic Leak - etiology ; Elective Surgical Procedures ; Female ; Follow-Up Studies ; Humans ; Laparoscopy ; Logistic Models ; Male ; Middle Aged ; Multivariate Analysis ; Neoplasm Staging ; Rectal cancer ; Rectal Neoplasms - mortality ; Rectal Neoplasms - pathology ; Rectal Neoplasms - surgery ; Rectum - surgery ; Retrospective Studies ; Risk Factors ; Sex Factors ; surgical site infection ; Surgical Wound Infection - epidemiology ; Surgical Wound Infection - etiology ; Treatment Outcome</subject><ispartof>Colorectal disease, 2012-03, Vol.14 (3), p.e95-e102</ispartof><rights>2011 The Authors. Colorectal Disease © 2011 The Association of Coloproctology of Great Britain and Ireland</rights><rights>2011 The Authors. Colorectal Disease © 2011 The Association of Coloproctology of Great Britain and Ireland.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5238-71284ce1605fef2f0883d04c6aec24dcb1295e9e4057484fb1cae5f4b7dcf3263</citedby><cites>FETCH-LOGICAL-c5238-71284ce1605fef2f0883d04c6aec24dcb1295e9e4057484fb1cae5f4b7dcf3263</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1463-1318.2011.02798.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1463-1318.2011.02798.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21883813$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Biondo, S.</creatorcontrib><creatorcontrib>Kreisler, E.</creatorcontrib><creatorcontrib>Fraccalvieri, D.</creatorcontrib><creatorcontrib>Basany, E. E.</creatorcontrib><creatorcontrib>Codina-Cazador, A.</creatorcontrib><creatorcontrib>Ortiz, H.</creatorcontrib><title>Risk factors for surgical site infection after elective resection for rectal cancer. A multivariate analysis on 2131 patients</title><title>Colorectal disease</title><addtitle>Colorectal Dis</addtitle><description>Aim Surgical site infection (SSI) is the most common cause of morbidity after colorectal surgery. The aim of this study was to analyze risk factors for SSI in patients who had undergone surgery for rectal cancer.
Method A multicentre observational study was carried out on 2131 patients operated on for rectal cancer between May 2006 and May 2009. Twenty‐nine centres were involved. SSI included wound infection and organ space infection within 30 days after the operation. Univariate and multivariate analyses were carried out to study possible risk factors for SSI.
Results Wound infection and organ space infection were diagnosed in 8.9% and 10%, respectively, of patients. The anastomotic leakage rate was 8%. Multivariate analysis showed that wound infection was related to tumour stage, a converted laparoscopic procedure and open surgery. Organ space infection was related to Stage IV tumour, a tumour < 11 cm from the anal verge, low anterior resection and Hartmann’s procedure.
Conclusion Rectal surgery for malignant disease is associated with a considerable rate of SSI. Wound infection and organ space infection are related to different factors and therefore should be evaluated separately.</description><subject>Adenocarcinoma - mortality</subject><subject>Adenocarcinoma - pathology</subject><subject>Adenocarcinoma - surgery</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anastomotic Leak - epidemiology</subject><subject>Anastomotic Leak - etiology</subject><subject>Elective Surgical Procedures</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Laparoscopy</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Neoplasm Staging</subject><subject>Rectal cancer</subject><subject>Rectal Neoplasms - mortality</subject><subject>Rectal Neoplasms - pathology</subject><subject>Rectal Neoplasms - surgery</subject><subject>Rectum - surgery</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Sex Factors</subject><subject>surgical site infection</subject><subject>Surgical Wound Infection - epidemiology</subject><subject>Surgical Wound Infection - etiology</subject><subject>Treatment Outcome</subject><issn>1462-8910</issn><issn>1463-1318</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE9vEzEQxS1ERUvhKyDfOO3isfeP94JUApRKVSpBEVIvluOMkdPNbvDstsmB7463SXPGFz9r3vt59BjjIHJI58Mqh6JSGSjQuRQAuZB1o_PtC3Z2HLx80jLTDYhT9ppoJQRUNehX7FSC1kqDOmN_vwe65966oY_EfR85jfF3cLblFAbkofPohtB33PoBI8d2ej4gj0iHwRSKSaeIs53DmPMLvh7bZLMx2ASxnW13FIgnt0y78Y0dAnYDvWEn3raEbw_3Ofv59cvt7Ft2fXN5Nbu4zlwplc5qkLpwCJUoPXrpRdp-KQpXWXSyWLoFyKbEBgtR1oUu_AKcxdIXi3rpvJKVOmfv99xN7P-MSINZB3LYtrbDfiTTSFHrSimRnHrvdLEniujNJoa1jTsDwkzdm5WZKjZTxWbq3jx1b7Yp-u7wybhY4_IYfC47GT7uDY-hxd1_g83s5vPVJBMg2wMCDbg9Amy8N1Wt6tL8ml-aat7M7z7d_TC36h_AKKOp</recordid><startdate>201203</startdate><enddate>201203</enddate><creator>Biondo, S.</creator><creator>Kreisler, E.</creator><creator>Fraccalvieri, D.</creator><creator>Basany, E. E.</creator><creator>Codina-Cazador, A.</creator><creator>Ortiz, H.</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201203</creationdate><title>Risk factors for surgical site infection after elective resection for rectal cancer. A multivariate analysis on 2131 patients</title><author>Biondo, S. ; Kreisler, E. ; Fraccalvieri, D. ; Basany, E. E. ; Codina-Cazador, A. ; Ortiz, H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5238-71284ce1605fef2f0883d04c6aec24dcb1295e9e4057484fb1cae5f4b7dcf3263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adenocarcinoma - mortality</topic><topic>Adenocarcinoma - pathology</topic><topic>Adenocarcinoma - surgery</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anastomotic Leak - epidemiology</topic><topic>Anastomotic Leak - etiology</topic><topic>Elective Surgical Procedures</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Laparoscopy</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Neoplasm Staging</topic><topic>Rectal cancer</topic><topic>Rectal Neoplasms - mortality</topic><topic>Rectal Neoplasms - pathology</topic><topic>Rectal Neoplasms - surgery</topic><topic>Rectum - surgery</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Sex Factors</topic><topic>surgical site infection</topic><topic>Surgical Wound Infection - epidemiology</topic><topic>Surgical Wound Infection - etiology</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Biondo, S.</creatorcontrib><creatorcontrib>Kreisler, E.</creatorcontrib><creatorcontrib>Fraccalvieri, D.</creatorcontrib><creatorcontrib>Basany, E. E.</creatorcontrib><creatorcontrib>Codina-Cazador, A.</creatorcontrib><creatorcontrib>Ortiz, H.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Colorectal disease</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Biondo, S.</au><au>Kreisler, E.</au><au>Fraccalvieri, D.</au><au>Basany, E. E.</au><au>Codina-Cazador, A.</au><au>Ortiz, H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Risk factors for surgical site infection after elective resection for rectal cancer. A multivariate analysis on 2131 patients</atitle><jtitle>Colorectal disease</jtitle><addtitle>Colorectal Dis</addtitle><date>2012-03</date><risdate>2012</risdate><volume>14</volume><issue>3</issue><spage>e95</spage><epage>e102</epage><pages>e95-e102</pages><issn>1462-8910</issn><eissn>1463-1318</eissn><abstract>Aim Surgical site infection (SSI) is the most common cause of morbidity after colorectal surgery. The aim of this study was to analyze risk factors for SSI in patients who had undergone surgery for rectal cancer.
Method A multicentre observational study was carried out on 2131 patients operated on for rectal cancer between May 2006 and May 2009. Twenty‐nine centres were involved. SSI included wound infection and organ space infection within 30 days after the operation. Univariate and multivariate analyses were carried out to study possible risk factors for SSI.
Results Wound infection and organ space infection were diagnosed in 8.9% and 10%, respectively, of patients. The anastomotic leakage rate was 8%. Multivariate analysis showed that wound infection was related to tumour stage, a converted laparoscopic procedure and open surgery. Organ space infection was related to Stage IV tumour, a tumour < 11 cm from the anal verge, low anterior resection and Hartmann’s procedure.
Conclusion Rectal surgery for malignant disease is associated with a considerable rate of SSI. Wound infection and organ space infection are related to different factors and therefore should be evaluated separately.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>21883813</pmid><doi>10.1111/j.1463-1318.2011.02798.x</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adenocarcinoma - mortality Adenocarcinoma - pathology Adenocarcinoma - surgery Adult Aged Aged, 80 and over Anastomotic Leak - epidemiology Anastomotic Leak - etiology Elective Surgical Procedures Female Follow-Up Studies Humans Laparoscopy Logistic Models Male Middle Aged Multivariate Analysis Neoplasm Staging Rectal cancer Rectal Neoplasms - mortality Rectal Neoplasms - pathology Rectal Neoplasms - surgery Rectum - surgery Retrospective Studies Risk Factors Sex Factors surgical site infection Surgical Wound Infection - epidemiology Surgical Wound Infection - etiology Treatment Outcome |
| title | Risk factors for surgical site infection after elective resection for rectal cancer. A multivariate analysis on 2131 patients |
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