Effect of soybean (Glycine max L.) on the hormonal milieu of male rats

Effect of soybean (Glycine max) on serum level of some sex hormones: testosterone, follicle stimulating hormone (FSH), luteinizing hormone/interstitial cell stimulating hormone (LH/ICSH), estradiol and prolactin in male rats was investigated. Twenty male albino rats of 12 weeks old with similar body...

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Veröffentlicht in:	Pakistan journal of biological sciences 2011-07, Vol.14 (14), p.752-754
Hauptverfasser:	Ekaluo, U B, Udoh, P B, Ikpeme, E V, Udensi, O
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Estradiol - blood Follicle Stimulating Hormone - blood Glycine max - chemistry Luteinizing Hormone - blood Male Plant Extracts - pharmacology Prolactin - blood Random Allocation Rats Testosterone - blood
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creator	Ekaluo, U B Udoh, P B Ikpeme, E V Udensi, O
description	Effect of soybean (Glycine max) on serum level of some sex hormones: testosterone, follicle stimulating hormone (FSH), luteinizing hormone/interstitial cell stimulating hormone (LH/ICSH), estradiol and prolactin in male rats was investigated. Twenty male albino rats of 12 weeks old with similar body weights were assigned to four groups of 5 rats each and treatment with soybean meal at 100, 200 and 300 mg kg(-1) body weight, respectively daily for 8 weeks. Blood samples collected through cardiac puncture were assayed for levels of hormones. There were dose-dependent effects of the soybean meal on the serum concentration of the hormones. The treatment significantly reduced the levels of testosterone and FSH in the serum while it significantly increased the levels of estradiol, LH/ICSH and prolactin. The results show that soybean (Glycine max) had strong capability to disrupt hormonal functions. Hence, its indiscriminate use could increase the risk of infertility in males.
doi_str_mv	10.3923/pjbs.2011.752.754
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Twenty male albino rats of 12 weeks old with similar body weights were assigned to four groups of 5 rats each and treatment with soybean meal at 100, 200 and 300 mg kg(-1) body weight, respectively daily for 8 weeks. Blood samples collected through cardiac puncture were assayed for levels of hormones. There were dose-dependent effects of the soybean meal on the serum concentration of the hormones. The treatment significantly reduced the levels of testosterone and FSH in the serum while it significantly increased the levels of estradiol, LH/ICSH and prolactin. The results show that soybean (Glycine max) had strong capability to disrupt hormonal functions. 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Twenty male albino rats of 12 weeks old with similar body weights were assigned to four groups of 5 rats each and treatment with soybean meal at 100, 200 and 300 mg kg(-1) body weight, respectively daily for 8 weeks. Blood samples collected through cardiac puncture were assayed for levels of hormones. There were dose-dependent effects of the soybean meal on the serum concentration of the hormones. The treatment significantly reduced the levels of testosterone and FSH in the serum while it significantly increased the levels of estradiol, LH/ICSH and prolactin. The results show that soybean (Glycine max) had strong capability to disrupt hormonal functions. 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source	MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Science Alert
subjects	Animals Estradiol - blood Follicle Stimulating Hormone - blood Glycine max - chemistry Luteinizing Hormone - blood Male Plant Extracts - pharmacology Prolactin - blood Random Allocation Rats Testosterone - blood
title	Effect of soybean (Glycine max L.) on the hormonal milieu of male rats
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