Insights from genomic comparisons of genetically monomorphic bacterial pathogens

Some of the most deadly bacterial diseases, including leprosy, anthrax and plague, are caused by bacterial lineages with extremely low levels of genetic diversity, the so-called ‘genetically monomorphic bacteria’. It has only become possible to analyse the population genetics of such bacteria since...

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Veröffentlicht in:	Philosophical transactions of the Royal Society of London. Series B. Biological sciences 2012-03, Vol.367 (1590), p.860-867
1. Verfasser:	Achtman, Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Ancient Dna Black Death Disease transmission Epidemics - history Evolution Evolution, Molecular Evolutionary genetics Genetic Variation Genetically Monomorphic Bacterial Pathogen Genetics, Population - methods Genome, Bacterial - genetics Genomes Historical Reconstruction History, 19th Century History, Ancient History, Medieval Human genetics Humans Medical genetics Microbial genetics Pandemics Pathogens Phylogeography Plague Plague - epidemiology Plague - microbiology Polymorphism, Single Nucleotide - genetics Review Selection, Genetic Staphylococcus aureus Yersinia pestis Yersinia pestis - genetics Yersinia pestis - pathogenicity
Online-Zugang:	Volltext
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