Development of N-Substituted Hydroxylamines as Efficient Nitroxyl (HNO) Donors

Due to its inherent reactivity, nitroxyl (HNO), must be generated in situ through the use of donor compounds, but very few physiologically useful HNO donors exist. Novel N-substituted hydroxylamines with carbon-based leaving groups have been synthesized, and their structures confirmed by X-ray cryst...

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Veröffentlicht in:	Journal of the American Chemical Society 2012-02, Vol.134 (4), p.1962-1965
Hauptverfasser:	Guthrie, Daryl A, Kim, Nam Y, Siegler, Maxime A, Moore, Cathy D, Toscano, John P
Format:	Artikel
Sprache:	eng
Schlagworte:	Crystallography, X-Ray Hydroxylamines - chemical synthesis Hydroxylamines - chemistry Models, Molecular Molecular Structure Nitrogen Oxides - chemical synthesis Nitrogen Oxides - chemistry
Online-Zugang:	Volltext
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