Lipid analysis of flat-mounted eye tissue by imaging mass spectrometry with identification of contaminants in preservation

Matrix-assisted laser desorption/ionization imaging mass spectrometry was used to analyze donor eye tissue specimens for phospholipid content to evaluate lipid distribution. Phosphatidylcholines and sphingomyelins were detected in the positive ion mode using 2,5-dihydroxybenzoic acid as the matrix....

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2011-07, Vol.401 (1), p.103-113
Hauptverfasser:	Garrett, Timothy J., Menger, Robert F., Dawson, William W., Yost, Richard A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical Chemistry Animals Biochemistry Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Classification Contaminants Eye - chemistry Eye - ultrastructure Food Science Haplorhini Humans Imaging Laboratory Medicine Lasers Lipids Mass spectrometry Mathematical analysis Monitoring/Environmental Analysis Monkeys Organ Preservation Original Paper Phospholipids - analysis Specimen Handling - methods Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods Spectrum analysis Surface active agents Tissue Banks
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