Developmentally regulated IL6-type cytokines signal to germ cells in the human fetal ovary

Fetal ovarian development and primordial follicle formation are imperative for adult fertility in the female. Data suggest the interleukin (IL)6-type cytokines, leukaemia inhibitory factor (LIF), IL6, oncostatin M (OSM) and ciliary neurotrophic factor (CNTF), are able to regulate the survival, proli...

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Veröffentlicht in:	Molecular human reproduction 2012-02, Vol.18 (2), p.88-95
Hauptverfasser:	Eddie, Sharon L., Childs, Andrew J., Jabbour, Henry N., Anderson, Richard A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Ciliary Neurotrophic Factor - genetics Ciliary Neurotrophic Factor - metabolism Cytokine Receptor gp130 - genetics Cytokine Receptor gp130 - metabolism Female Fetus Gene Expression Regulation, Developmental Gestational Age Humans Interleukin-6 - genetics Interleukin-6 - metabolism Leukemia Inhibitory Factor - genetics Leukemia Inhibitory Factor - metabolism Oncostatin M - genetics Oncostatin M - metabolism Oocytes - growth & development Oocytes - metabolism Ovarian Follicle - growth & development Ovarian Follicle - metabolism Pregnancy Pregnancy Trimesters Real-Time Polymerase Chain Reaction Receptor, Ciliary Neurotrophic Factor - genetics Receptor, Ciliary Neurotrophic Factor - metabolism Receptors, Oncostatin M - genetics Receptors, Oncostatin M - metabolism RNA, Messenger - biosynthesis Signal Transduction - genetics
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